Evidence map›Paper›PMID 32635889›Full record

Observational studyBMC emergency medicine2020

Prehospital administration of blood products: experiences from a Finnish physician-staffed helicopter emergency medical service.

Pauli Vuorinen, Joonas-Eemeli Kiili, Piritta Setälä, Antti Kämäräinen, Sanna Hoppu

Abstract readObservational Study
In one paragraph

Observational study in BMC emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Physician-staffed prehospital units for severely injured patients in the Stockholm trauma system - is there a survival benefit?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  3. Pre-hospital assessment of trauma associated severe hemorrhage (phTASH) - analysis of TraumaRegister DGUScandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pauli VuorinenEmergency Medical Services, Tampere University Hospital, PO Box 2000, FI-33521, Tampere, Finland. pauli.e.vuorinen@pshp.fi.ORCID 0000-0003-3305-7356
Joonas-Eemeli KiiliEmergency Medical Services, Tampere University Hospital, PO Box 2000, FI-33521, Tampere, Finland.
Piritta SetäläEmergency Medical Services, Tampere University Hospital, PO Box 2000, FI-33521, Tampere, Finland.
Antti KämäräinenEmergency Medical Services, Tampere University Hospital, PO Box 2000, FI-33521, Tampere, Finland.
Sanna HoppuEmergency Medical Services, Tampere University Hospital, PO Box 2000, FI-33521, Tampere, Finland.

Funding

Tays 9V006
6 · The paper itself

Abstract

backgroundMassive infusions of crystalloids into bleeding hypotensive patients can worsen the outcome. Military experience suggests avoiding crystalloids using early damage control resuscitation with blood components in out of hospital setting. Civilian emergency medical services have since followed this idea. We describe our red blood cell protocol in helicopter emergency medical services (HEMS) and initial experience with prehospital blood products from the first 3 years after implementation.

methodsWe performed an observational study of patients attended by the HEMS unit between 2015 and 2018 to whom packed red blood cells, freeze-dried plasma, or both were transfused. The Student's two-sided T-test was used to compare vitals in prehospital phase with those at the hospital's emergency department. A p-value < 0.05 was considered significant.

resultsAltogether, 62 patients received prehospital transfusions. Of those, 48 (77%) were trauma patients and most (n = 39, 81%) suffered blunt trauma. The transfusion began at a median of 33 (IQR 21-47) minutes before hospital arrival. Median systolic blood pressure showed an increase from 90 mmHg (IQR 75-111 mmHg) to 107 mmHg (IQR 80-124 mmHg; P < 0.026) during the prehospital phase. Four units of red blood cells were handled incorrectly when unused red blood cells were returned and required disposal during a three-year period. There were no reported adverse effects from prehospital transfusions.

conclusionWe treated two patients per month with prehospital blood products. A prehospital physician-staffed HEMS unit carrying blood products is a feasible and safe method to start transfusion roughly 30 min before arrival to the hospital.

trial registrationThe study was retrospectively registered by the Tampere University Hospital's Medical Director (R19603) 5.11.2019.

Indexed as

Air AmbulancesAdultAgedAircraftBlood TransfusionEmergency Medical ServicesFemaleFinlandHumansMaleMiddle AgedPractice Patterns, Physicians'Retrospective StudiesFreeze dried plasmaHelicopter emergency medical servicesHEMSPrehospital blood productsRed blood cells

Identifiers

PMID32635889
PMCPMC7341661

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.