Evidence map›Paper›PMID 32635785›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2020

Synthesis and structure-activity relationships of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives as 5-lipoxygenase inhibitors.

Oludotun A Phillips, Mira A Bosso, Charles I Ezeamuzie

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Oludotun A PhillipsFaculty of Pharmacy, Department of Pharmaceutical Chemistry, Kuwait University, Safat, Kuwait.ORCID https://orcid.org/0000-0002-8350-7338
Mira A BossoFaculty of Medicine, Department of Pharmacology & Toxicology, Kuwait University, Safat, Kuwait.
Charles I EzeamuzieFaculty of Medicine, Department of Pharmacology & Toxicology, Kuwait University, Safat, Kuwait.
Kuwait University · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxazolidinone hydroxamic acid derivatives were synthesised and evaluated for inhibitory activity against leukotriene (LT) biosynthesis in three

Indexed as

AnimalsAnti-Inflammatory Agents, Non-SteroidalArachidonate 5-LipoxygenaseCell LineDisease Models, AnimalDose-Response Relationship, DrugFemaleHumansHydroxamic AcidsInflammationLeukotriene B4Lipoxygenase InhibitorsMaleMiceMice, Inbred BALB CMolecular StructureAnti-Inflammatory Agents, Non-SteroidalArachidonate 5-LipoxygenaseHydroxamic AcidsLeukotriene B4Lipoxygenase InhibitorsOxazolidinonesZymosan5-lipoxygenase inhibitorsHydroxamic acid derivativesleukotrienesoxazolidinone-hydroxamates

Identifiers

PMID32635785
PMCPMC7470027
OpenAlexW3041449817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.