Evidence map›Paper›PMID 32635721›Full record

ArticleChemical research in toxicology2020

Hot Wires and Film Boiling: Another Look at Carbonyl Formation in Electronic Cigarettes.

Soha Talih, Rola Salman, Ebrahim Karam, Mario El-Hourani, Rachel El-Hage, Nareg Karaoghlanian, Ahmad El-Hellani, Najat Saliba, Alan Shihadeh

Open access · greenAbstract read
In one paragraph

Article in Chemical research in toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 0 citations in OpenAlex.

  1. Health Hazards of E-Cigarettes and Heated Tobacco Products: a Comprehensive Analysis of Hazardous Substances and Regulatory Gaps.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Pooled it
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  4. Review
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  11. Passive Vaping from Sub-Ohm Electronic Cigarette Devices.International journal of environmental research and public health · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Soha TalihMechanical Engineering Department, Faculty of Engineering and Architecture, American University of Beirut, Bliss Street, P.O. Box 11-0236, Beirut 1107 2020, Lebanon.ORCID http://orcid.org/0000-0002-3520-675X
Rola SalmanMechanical Engineering Department, Faculty of Engineering and Architecture, American University of Beirut, Bliss Street, P.O. Box 11-0236, Beirut 1107 2020, Lebanon.
Ebrahim KaramMechanical Engineering Department, Faculty of Engineering and Architecture, American University of Beirut, Bliss Street, P.O. Box 11-0236, Beirut 1107 2020, Lebanon.
Mario El-HouraniMechanical Engineering Department, Faculty of Engineering and Architecture, American University of Beirut, Bliss Street, P.O. Box 11-0236, Beirut 1107 2020, Lebanon.
Rachel El-HageChemistry Department, Faculty of Arts and Sciences, American University of Beirut, Bliss Street, P.O. Box 11-0236, Beirut 1107 2020, Lebanon.
Nareg KaraoghlanianMechanical Engineering Department, Faculty of Engineering and Architecture, American University of Beirut, Bliss Street, P.O. Box 11-0236, Beirut 1107 2020, Lebanon.
Ahmad El-HellaniChemistry Department, Faculty of Arts and Sciences, American University of Beirut, Bliss Street, P.O. Box 11-0236, Beirut 1107 2020, Lebanon.
Najat SalibaChemistry Department, Faculty of Arts and Sciences, American University of Beirut, Bliss Street, P.O. Box 11-0236, Beirut 1107 2020, Lebanon.ORCID http://orcid.org/0000-0002-4276-1524
Alan ShihadehMechanical Engineering Department, Faculty of Engineering and Architecture, American University of Beirut, Bliss Street, P.O. Box 11-0236, Beirut 1107 2020, Lebanon.
Virginia Commonwealth University · US

Funding

Project 4: Using a prospective cohort survey to test population-level predictions generated by Projects 1-3U54DA036105 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI FAGAN, PEBBLES · 2018 to 2022
$20.8M
NIDA NIH HHS U54 DA036105
6 · The paper itself

Abstract

Electronic cigarettes (ECIGs) are a class of tobacco products that emit a nicotine-containing aerosol by heating and vaporizing a liquid. Apart from initiating nicotine addiction in nonsmokers, a persistent concern about these products is that their emissions often include high levels of carbonyl species, toxicants thought to cause most noncancer pulmonary diseases in smokers. This study examined whether the phenomenon of film boiling can account for observations of high carbonyl emissions under certain operating conditions and, if so, whether film boiling theory can be invoked to predict conditions where high carbonyl emissions are likely. We measured the critical heat flux for several common heating materials and liquids and carbonyl emissions for several ECIG types while varying the power. We found that emissions rise drastically whenever the power exceeds the value corresponding to the critical heat flux. While limiting the heat flux to below this threshold can greatly reduce carbonyl exposure, ECIG manufacturer operating instructions often exceed it. Product regulations that limit heat flux may reduce the public health burden of electronic cigarette use.

Identifiers

PMID32635721
PMCPMC9355290
OpenAlexW3023746151

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.