ArticleJournal of clinical medicine2020
Nomogram Predicting the Likelihood of Parametrial Involvement in Early-Stage Cervical Cancer: Avoiding Unjustified Radical Hysterectomies.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- [Epidemiological characteristics and the establishment and evaluation of a risk prediction model for nosocomial infection in burn patients].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Trial
- Prognostic utility of systemic immune-inflammation markers in locally advanced cervical cancer undergoing radical radiotherapy.The oncologist · 2026Article
- Development and validation of nomogram models for predicting overall survival and cancer-specific survival in gastric cancer patients with liver metastases: a cohort study based on the SEER database.American journal of cancer research · 2024Article
- Impact of therapeutic strategy on disease-free and overall survival of early-stage cervical cancer: Surgery alone versus preoperative radiation.Cancer reports (Hoboken, N.J.) · 2023Article
- Clavien-Dindo classification and risk prediction model of complications after robot-assisted radical hysterectomy for cervical cancer.Journal of robotic surgery · 2023Article
- Comparison of nomogram and machine-learning methods for predicting the survival of non-small cell lung cancer patients.Cancer innovation · 2022Article
- What are the determinants of parametrial invasion in patients with early stage cervical cancer: A cross sectional study.Annals of medicine and surgery (2012) · 2022Article
- Lymph Node Involvement in Early-Stage Cervical Cancer: Is Lymphangiogenesis a Risk Factor? Results from the MICROCOL Study.Cancers · 2022Article
- Predicting the Recurrence of Operable Cervical Cancer Patients Based on Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) Score and Classical Clinicopathological Parameters.Journal of inflammation research · 2022Article
- Development and validation of a prognostic nomogram for 2018 FIGO stages IB1, IB2, and IIA1 cervical cancer: a large multicenter study.Annals of translational medicine · 2022Article
- Sentinel Node Biopsy by Transvaginal Natural Orifice Transluminal Endoscopic Surgery in a Patient with Early-Stage Cervical Cancer: A Case Report.Case reports in oncologyArticle
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to establish a tool predicting parametrial involvement (PI) in patients with early-stage cervical cancer and select a sub-group of patients who would most benefit from a less radical surgery.
methodsWe retrospectively reviewed patients from two prospective multicentric databases-SENTICOL I and II-from 2005 to 2012. Patients with early-stage cervical cancer (FIGO 2018 IA with lympho-vascular involvement to IIA1), undergoing radical surgery (hysterectomy or trachelectomy) with bilateral sentinel lymph node (SLN) mapping with no metastatic node or PI on pre-operative imaging, were included.
resultsIn total, 5.2% patients (11/211) presented a histologic PI. After univariate analysis, SLN status, lympho-vascular space invasion, deep stromal invasion and tumor size were significantly associated with PI and were included in our nomogram. Our predictive model had an AUC of 0.92 (IC95% = 0.86-0.98) and presented a good calibration. A low risk group, defined according to the optimal sensitivity and specificity, presented a predicted probability of PI of 2%.
conclusionPatients could benefit from a two-step approach. Final surgery (i.e. radical surgery and/or lymphadenectomy) would depend on the SLN status and the probability PI calculated after an initial conization with bilateral SLN mapping.
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