Evidence map›Paper›PMID 32635588›Full record

ArticleMicroorganisms2020

Relationship between the Oral and Vaginal Microbiota of South African Adolescents with High Prevalence of Bacterial Vaginosis.

Christina Balle, Rachel Esra, Enock Havyarimana, Shameem Z Jaumdally, Katie Lennard, Iyaloo N Konstantinus, Shaun L Barnabas, Anna-Ursula Happel, Katherine Gill, Tanya Pidwell and 5 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Article
  3. Modulation of NK Cell Properties by ESKAPE Group Bacteria.International journal of molecular sciences · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. The Role ofPathogens (Basel, Switzerland) · 2024
    Review
  9. Article
  10. Review
  11. Female reproductive tract-organ axes.Frontiers in immunology · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Christina BalleDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 7925 Cape Town, South Africa.ORCID 0000-0003-3439-3992
Rachel EsraDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 7925 Cape Town, South Africa.ORCID 0000-0002-7668-1792
Enock HavyarimanaDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 7925 Cape Town, South Africa.
Shameem Z JaumdallyDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 7925 Cape Town, South Africa.
Katie LennardDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 7925 Cape Town, South Africa.ORCID 0000-0002-7801-1063
Iyaloo N KonstantinusDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 7925 Cape Town, South Africa.
Shaun L BarnabasDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 7925 Cape Town, South Africa.
Anna-Ursula HappelDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 7925 Cape Town, South Africa.
Katherine GillDesmond Tutu HIV Centre, University of Cape Town, 7925 Cape Town, South Africa.ORCID 0000-0002-3372-9506
Tanya PidwellDesmond Tutu HIV Centre, University of Cape Town, 7925 Cape Town, South Africa.
Jairam R LingappaUniversity of Washington Departments of Pediatrics and Global Health, 98195 Seattle, WA, USA.
Hoyam GamieldienDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 7925 Cape Town, South Africa.
Linda-Gail BekkerDesmond Tutu HIV Centre, University of Cape Town, 7925 Cape Town, South Africa.
Jo-Ann S PassmoreDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 7925 Cape Town, South Africa.
Heather B JaspanDepartment of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 7925 Cape Town, South Africa.ORCID 0000-0002-0745-6073
University of Cape Town · ZADesmond Tutu HIV Foundation · ZANational Health Laboratory Service · ZAUniversity of Washington · US

Funding

CHAMPS: Choices for Adolescent Methods of Prevention in South AfricaR01AI094586 · NIAID · DESMOND TUTU HIV FOUNDATION · PI BEKKER, LINDA-GAIL GAIL · 2011 to 2014
$2.5M
Hormone induced mucosal susceptibility and HIV risk in South African adolescentsR01HD083040 · NICHD · UNIVERSITY OF CAPE TOWN · PI JASPAN, HEATHER BERYL, PASSMORE, JO-ANN SHELLEY · 2015 to 2019
$1.9M
NICHD NIH HHS R01 HD083040NIH HHS R01AI094586NIH HHS R01HD083040
6 · The paper itself

Abstract

Bacterial vaginosis (BV) and periodontal disease (PD) are characterised as bacterial dysbioses. Both are associated with an increased risk of poor pregnancy outcomes, yet it is unknown whether PD and BV are related. We characterised the oral microbiota of young South African females with a high prevalence of BV and investigated the association between oral communities and vaginal microbiota. DNA was extracted from vaginal lateral wall, saliva and supragingival plaque samples from 94 adolescent females (aged 15-19 years). 16S rRNA gene sequencing of the V4 hypervariable region was performed for analysis of the oral and vaginal microbiota and BV status was determined by Nugent scoring. The core oral microbiota was predominately comprised of Firmicutes followed by Proteobacteria and Bacteroidetes. The salivary microbiota of participants with BV was more diverse than those with lactobacillus-dominated communities (

Indexed as

adolescentsbacterial vaginosismicrobiotaoralperiodontitisSouth Africa

Identifiers

PMID32635588
PMCPMC7409319
OpenAlexW3038998259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.