Evidence map›Paper›PMID 32635579›Full record

Observational studyInternational journal of environmental research and public health2020

Upper and Lower Limb Strength and Body Posture in Children with Congenital Hypothyroidism: An Observational Case-Control Study.

Jessica Brusa, Maria Cristina Maggio, Valerio Giustino, Ewan Thomas, Daniele Zangla, Angelo Iovane, Antonio Palma, Giovanni Corsello, Giuseppe Messina, Marianna Bellafiore

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jessica BrusaDepartment of Psychology, Educational Science and Human Movement, University of Palermo, 90144 Palermo, Italy.
Maria Cristina MaggioDepartment of Health Promotion Sciences, Maternal and Infantile Care, Internal Medicine and Medical Specialities "G. D'Alessandro", University of Palermo, 90127 Palermo, Italy.
Valerio GiustinoDepartment of Psychology, Educational Science and Human Movement, University of Palermo, 90144 Palermo, Italy.ORCID 0000-0002-4575-8021
Ewan ThomasDepartment of Psychology, Educational Science and Human Movement, University of Palermo, 90144 Palermo, Italy.ORCID 0000-0001-5991-8316
Daniele ZanglaDepartment of Psychology, Educational Science and Human Movement, University of Palermo, 90144 Palermo, Italy.
Angelo IovaneDepartment of Psychology, Educational Science and Human Movement, University of Palermo, 90144 Palermo, Italy.
Antonio PalmaDepartment of Psychology, Educational Science and Human Movement, University of Palermo, 90144 Palermo, Italy.
Giovanni CorselloDepartment of Health Promotion Sciences, Maternal and Infantile Care, Internal Medicine and Medical Specialities "G. D'Alessandro", University of Palermo, 90127 Palermo, Italy.
Giuseppe MessinaDepartment of Psychology, Educational Science and Human Movement, University of Palermo, 90144 Palermo, Italy.
Marianna BellafioreDepartment of Psychology, Educational Science and Human Movement, University of Palermo, 90144 Palermo, Italy.ORCID 0000-0002-3092-1666
University of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCongenital hypothyroidism (CH) is an endocrine disease with a precocious significant impairment of growth and neuromotor development. Thyroid hormones are essential for central nervous system development, maturation, and myelination. Furthermore, thyroid hormone deficiency affects the function of several systems, including the musculoskeletal system. The disease has a significant incidence in the general population (1:3000-1:2000 newborns in Italy). The aim of the present study was to evaluate any differences in upper and lower limb strength, body sway, and plantar loading distribution in children with CH compared to healthy children.

methodsIn this study, the case group was composed of children with CH (CHG), while the control group included healthy children (CG). Both groups comprised 19 children (CHG: female = 12; CG: female = 9). The maximum isometric handgrip strength and explosive-elastic lower limb strength were assessed with the handgrip test and the Sargent test, respectively. The stabilometric and baropodometric analyses were used to measure the Center of Pressure displacements and the plantar loading distribution between feet, respectively. The differences between groups were analyzed by a univariate analysis of covariance using as covariates weight and height with the significant level set at < 0.05.

resultsWe found that CHG children were shorter and thinner than CG ones (

conclusionsThese findings seem to suggest that CH does not affect muscle strength in early treated children. However, these patients show poor postural control ability and asymmetric plantar loading distribution. Increasing the physical activity in these children could improve their body posture.

Indexed as

Postural BalanceAdolescentCase-Control StudiesChildCongenital HypothyroidismFemaleHand StrengthHumansItalyMaleMuscle, SkeletalPosturebody swaycongenital hypothyroidismhandgrip testmuscle strengthplantar pressurepostureSargent test

Identifiers

PMID32635579
PMCPMC7370191
OpenAlexW3040005164

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.