Evidence map›Paper›PMID 32635522›Full record

ArticleMolecules (Basel, Switzerland)2020

Effects of Sesamin, the Major Furofuran Lignan of Sesame Oil, on the Amplitude and Gating of Voltage-Gated Na

Ping-Chung Kuo, Zi-Han Kao, Shih-Wei Lee, Sheng-Nan Wu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. The Evidence for Effective Inhibition ofInternational journal of molecular sciences · 2022
    Article
  6. Activation of Voltage-Gated NaBiomedicines · 2022
    Article
  7. Article
  8. Lignans of Sesame (Molecules (Basel, Switzerland) · 2021
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ping-Chung KuoSchool of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.ORCID 0000-0003-3019-1138
Zi-Han KaoDepartment of Physiology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
Shih-Wei LeeDepartment of Physiology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
Sheng-Nan WuDepartment of Physiology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.ORCID 0000-0002-5208-3253

Funding

Ministry of Sciences and Technology, Taiwan MOST-108-2314-B-006-094
6 · The paper itself

Abstract

Sesamin (SSM) and sesamolin (SesA) are the two major furofuran lignans of sesame oil and they have been previously noticed to exert various biological actions. However, their modulatory actions on different types of ionic currents in electrically excitable cells remain largely unresolved. The present experiments were undertaken to explore the possible perturbations of SSM and SesA on different types of ionic currents, e.g., voltage-gated Na

Indexed as

Ion Channel GatingAdenomaAnimalsAntioxidantsDioxolesLignansPituitary NeoplasmsPotassium Channels, Voltage-GatedRatsSesame OilTumor Cells, CulturedVoltage-Gated Sodium ChannelsAntioxidantsDioxolesLignansPotassium Channels, Voltage-GatedSesame OilsesaminVoltage-Gated Sodium Channelscurrent kineticserg-mediated K+ currentM-type K+ currentNa+ currentsesaminsesamolinsimulation model

Identifiers

PMID32635522
PMCPMC7411736

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.