Evidence map›Paper›PMID 32635494›Full record

Trial reportNutrients2020

Phytoplankton Supplementation Lowers Muscle Damage and Sustains Performance across Repeated Exercise Bouts in Humans and Improves Antioxidant Capacity in a Mechanistic Animal.

Matthew Sharp, Kazim Sahin, Matthew Stefan, Cemal Orhan, Raad Gheith, Dallen Reber, Nurhan Sahin, Mehmet Tuzcu, Ryan Lowery, Shane Durkee and 1 more

Erratum issuedAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Modulatory Effects ofFoods (Basel, Switzerland) · 2025
    Article
  4. Antioxidants (Basel, Switzerland) · 2025
    Article
  5. The Potential of Superoxide Dismutase-RichInternational journal of molecular sciences · 2025
    Review
  6. TetraSODNutrients · 2022
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Matthew SharpThe Applied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.ORCID 0000-0003-2018-9229
Kazim SahinAnimal Nutrition Department, School of Veterinary Medicine, Firat University, Elazig 23200, Turkey.ORCID 0000-0001-9542-5244
Matthew StefanThe Applied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.
Cemal OrhanAnimal Nutrition Department, School of Veterinary Medicine, Firat University, Elazig 23200, Turkey.ORCID 0000-0003-4138-7689
Raad GheithThe Applied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.
Dallen ReberThe Applied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.
Nurhan SahinAnimal Nutrition Department, School of Veterinary Medicine, Firat University, Elazig 23200, Turkey.
Mehmet TuzcuAnimal Nutrition Department, School of Veterinary Medicine, Firat University, Elazig 23200, Turkey.
Ryan LoweryThe Applied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.
Shane DurkeeLonza Consumer Health Inc., Morristown, NJ 07960, USA.
Jacob WilsonThe Applied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.

Funding

Lonza Consumer Health Inc. (Morrison, NJ, USA) N/A
6 · The paper itself

Abstract

The purpose of this study was to investigate the impact of antioxidant-rich marine phytoplankton supplementation (Oceanix, OCX) on performance and muscle damage following a cross-training event in endurance-trained subjects. Additionally, an animal model was carried out to assess the effects of varying dosages of OCX, with exercise, on intramuscular antioxidant capacity.

methodsIn the human trial, endurance-trained subjects (average running distance = 29.5 ± 2.6 miles × week

resultsFor the human trial, SJ power lowered in PLA relative to OCX at 24 h Post (-15%,

conclusionsPhytoplankton supplementation (Oceanix) sustains performance and lowers muscle damage across repeated exercise bouts. The ingredient appears to operate through an elevating oxidative capacity in skeletal muscle.

Indexed as

Dietary SupplementsPhytoplanktonAdultAnimalsAntioxidantsCatalaseCreatine KinaseDose-Response Relationship, DrugEndurance TrainingExerciseFemaleGlutathione PeroxidaseHumansIsometric ContractionMaleMuscle, SkeletalAntioxidantsCatalaseCreatine KinaseGlutathione PeroxidaseMyoglobinSuperoxide Dismutaseantioxidantsmuscle damagemuscle recoverymuscle sorenessphytoplankton

Identifiers

PMID32635494
PMCPMC7400322

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.