ArticleJournal of clinical medicine2020
Frailty and COVID-19: A Systematic Scoping Review.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association of frailty with outcomes in individuals with COVID-19: A living review and meta-analysis.Journal of the American Geriatrics Society · 2021Pooled it
- What is the relationship between validated frailty scores and mortality for adults with COVID-19 in acute hospital care? A systematic review.Age and ageing · 2021Pooled it
- The Impact of Frailty on COVID-19 Outcomes: A Systematic Review and Meta-analysis of 16 Cohort Studies.The journal of nutrition, health & aging · 2021Pooled it
- Enhancing Driving Ability in Older Adults through Health Exercises and Physical Activity: A Randomized Controlled Trial.International journal of environmental research and public health · 2023Trial
- An Easy-to-Implement Clinical-Trial Frailty Index Based on Accumulation of Deficits: Validation in Zoster Vaccine Clinical Trials.Clinical interventions in aging · 2022Trial
- Machine learning algorithms to predict frailty in older adults in China: a cross-sectional study.BMC geriatrics · 2025Article
- Frailty associated with nutritional status, functionality, physical activity and socioeconomic level, in older adults in Ecuador, post-pandemic.BMC geriatrics · 2025Article
- Association between a geriatric measure tool and adverse outcomes among older adults treated in an emergency department: a retrospective cohort study.Internal and emergency medicine · 2025Observational
- Frailty in older adults admitted to hospital: a six-year dual-centre retrospective study of over 53 000 clinical frailty scale assessments.Age and ageing · 2025Observational
- Role of Frailty Index-Laboratory to predict COVID-19 mortality: a prospective study.Frontiers in public health · 2025Article
- Impairment of the Functional Status and Decrease in Albumin in Frail Older People After a COVID-19 Outbreak: A Descriptive Study in a Long-Term Care Facility in Chile.Geriatrics (Basel, Switzerland) · 2024Article
- COVID-19-Associated Outcomes of Critical Illness in Patients with Frailty: a Cohort Study.Canadian geriatrics journal : CGJ · 2024Article
- Frailty after COVID-19: The wave after?Aging medicine (Milton (N.S.W)) · 2023Review
- COVID-19 and Frailty.Vaccines · 2023Review
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- Geriatric syndromes and functions in older adults with COVID-19 hospitalized in sub-acute care: a multicenter study.Aging clinical and experimental research · 2023Observational
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- Early Access to Oral Antivirals in High-Risk Outpatients: Good Weapons to Fight COVID-19.Viruses · 2022Article
- The role of the socio-economic context in the spread of the first wave of COVID-19 in the Marche Region (central Italy).International journal of disaster risk reduction : IJDRR · 2022Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Older people have paid a huge toll in terms of mortality during the coronavirus disease-19 (COVID-19) pandemic. Frailty may have contributed to the vulnerability of older people to more severe clinical presentation. We aimed at reviewing available evidence about frailty and COVID-19. We searched PUBMED, Web of Science, and EMBASE from 1 December 2019 to 29 May 2020. Study selection and data extraction were performed by three independent reviewers. Qualitative synthesis was conducted and quantitative data extracted when available. Forty papers were included: 13 editorials, 15 recommendations/guidelines, 3 reviews, 1 clinical trial, 6 observational studies, 2 case reports. Editorials and reviews underlined the potential clinical relevance of assessing frailty among older patients with COVID-19. However, frailty was only investigated in regards to its association with overall mortality, hospital contagion, intensive care unit admission rates, and disease phenotypes in the few observational studies retrieved. Specific interventions in relation to frailty or its impact on COVID-19 treatments have not been evaluated yet. Even with such limited evidence, clinical recommendations on the use of frailty tools have been proposed to support decision making about escalation plan. Ongoing initiatives are expected to improve knowledge of COVID-19 interaction with frailty and to promote patient-centered approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.