Evidence map›Paper›PMID 32635428›Full record

ReviewCancers2020

Intercellular Mitochondrial Transfer in the Tumor Microenvironment.

Hana Sahinbegovic, Tomas Jelinek, Matous Hrdinka, Juli R Bago, Marcello Turi, Tereza Sevcikova, Amina Kurtovic-Kozaric, Roman Hajek, Michal Simicek

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Mitochondrial transfer in tunneling nanotubes-a new target for cancer therapy.Journal of experimental & clinical cancer research : CR · 2024
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Mitochondrial transplantation and transfer: The promising method for diseases.Turkish journal of biology = Turk biyoloji dergisi · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Hana SahinbegovicDepartment of Clinical Studies, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic.
Tomas JelinekDepartment of Clinical Studies, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic.ORCID 0000-0002-5467-9253
Matous HrdinkaDepartment of Clinical Studies, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic.
Juli R BagoDepartment of Clinical Studies, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic.
Marcello TuriDepartment of Clinical Studies, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic.ORCID 0000-0002-8760-1794
Tereza SevcikovaDepartment of Clinical Studies, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic.
Amina Kurtovic-KozaricFaculty of Genetics and Bioengineering, International Burch University, 71210 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0002-6063-7260
Roman HajekDepartment of Clinical Studies, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic.
Michal SimicekDepartment of Clinical Studies, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic.ORCID 0000-0003-2388-2723
University of Ostrava · CZInternational Burch University · BA

Funding

ERDF-Project ENOCH No. CZ.02.1.01/0.0/0.0/16_019/0000868ERDF-Project New Directions of Biomedical Research in the Ostrava Region No. CZ.02.1.01/0.0/0.0/18_069/0010060Grantová Agentura České Republiky GA CR 19-25354YInstitutional Development Plan of University of Ostrava project no. IRP03_2018-2020University of Ostrava SGS03/LF/2019-2020 and SGS03/PrF/2019-2020
6 · The paper itself

Abstract

Cell-to-cell communication is a fundamental process in every multicellular organism. In addition to membrane-bound and released factors, the sharing of cytosolic components represents a new, poorly explored signaling route. An extraordinary example of this communication channel is the direct transport of mitochondria between cells. In this review, we discuss how intercellular mitochondrial transfer can be used by cancer cells to sustain their high metabolic requirements and promote drug resistance and describe relevant molecular players in the context of current and future cancer therapy.

Indexed as

cancermitochondriamitochondrial transfertumor microenvironmenttunneling nanotubes

Identifiers

PMID32635428
PMCPMC7407231
OpenAlexW3038245524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.