Evidence map›Paper›PMID 32635402›Full record

ArticleInsects2020

RNAi in Insects: A Revolution in Fundamental Research and Pest Control Applications.

Olivier Christiaens, Jinzhi Niu, Clauvis Nji Tizi Taning

Open access · goldAbstract readEditorial
In one paragraph

Article in Insects, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 94 citations in OpenAlex.

  1. Design of Lipopeptides and dsRNA-Lipopeptide Complexes for Sprayable RNAi-Based Plant Protection.Journal of peptide science : an official publication of the European Peptide Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. EndophyticJournal of fungi (Basel, Switzerland) · 2026
    Article
  7. Article
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  14. Reduction in Gonad Development and Sperm Motility in Male Brown PlanthopperInternational journal of molecular sciences · 2025
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Effect of silencingFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Olivier ChristiaensDepartment of Plants and Crops, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0001-5850-340X
Jinzhi NiuKey Laboratory of Entomology and Pest Control Engineering, College of Plant Protection, Southwest University, Chongqing 400716, China.
Clauvis Nji Tizi TaningDepartment of Plants and Crops, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-7597-1261
Ghent University · BESouthwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this editorial for the Special Issue on 'RNAi in insect pest control', three important applications of RNA interference (RNAi) in insects are briefly discussed and linked to the different studies published in this Special Issue. The discovery of the RNAi mechanism revolutionized entomological research, as it presented researchers with a tool to knock down genes, which is easily applicable in a wide range of insect species. Furthermore, RNAi also provides crop protection with a novel and promising pest control mode-of-action. The sequence-dependent nature allows RNAi-based control strategies to be highly species selective and the active molecule, a natural biological molecule known as double-stranded RNA (dsRNA), has a short environmental persistence. However, more research is needed to investigate different cellular and physiological barriers, such as cellular uptake and dsRNA degradation in the digestive system in insects, in order to provide efficient control methods against a wide range of insect pest species. Finally, the RNAi pathway is an important part of the innate antiviral immune defence of insects, and could even lead to applications targeting viruses in beneficial insects such as honeybees in the future.

Indexed as

antiviral immunitycrop protectiongene silencingloss-of-function analysisRNA interference

Identifiers

PMID32635402
PMCPMC7411770
OpenAlexW3039313974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.