Evidence map›Paper›PMID 32635357›Full record

ArticleCancers2020

Elective Neck Dissection or Sentinel Lymph Node Biopsy in Early Stage Oral Cavity Cancer Patients: The Dutch Experience.

Inne J den Toom, Koos Boeve, Daphne Lobeek, Elisabeth Bloemena, Maarten L Donswijk, Bart de Keizer, W Martin C Klop, C René Leemans, Stefan M Willems, Robert P Takes and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 81 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Inne J den ToomDepartment of Head and Neck Surgical Oncology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Koos BoeveDepartment of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Daphne LobeekDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Elisabeth BloemenaDepartment of Oral and Maxillofacial Surgery/Oral Pathology, Amsterdam UMC/Academic Centre for Dentistry (ACTA), 1081 HV Amsterdam, The Netherlands.ORCID 0000-0002-0221-9538
Maarten L DonswijkDepartment of Nuclear Medicine, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0003-2028-9713
Bart de KeizerDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.ORCID 0000-0002-6270-9483
W Martin C KlopDepartment of Head and Neck Surgery, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
C René LeemansDepartment of Otolaryngology-Head and Neck Surgery, Amsterdam UMC (location VU University Medical Center), 1081 HV Amsterdam, The Netherlands.
Stefan M WillemsDepartment of Pathology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
Robert P TakesDepartment of Otolaryngology-Head and Neck Surgery, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0003-4784-0499
Max J H WitjesDepartment of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Remco de BreeDepartment of Head and Neck Surgical Oncology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.ORCID 0000-0001-7128-5814
University Medical Center Groningen · NLUniversity Medical Center Utrecht · NLRadboud University Nijmegen · NLThe Netherlands Cancer Institute · NLAcademic Center for Dentistry Amsterdam · NLAmsterdam UMC Location Vrije Universiteit Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSentinel lymph node biopsy (SLNB) has been introduced as a diagnostic staging modality for detection of occult metastases in patients with early stage oral cancer. Comparisons regarding accuracy to the routinely used elective neck dissection (END) are lacking in literature.

methodsA retrospective, multicenter cohort study included 390 patients staged by END and 488 by SLNB.

resultsThe overall sensitivity (84% vs. 81%,

conclusionIn the absence of randomized clinical trials, this study provides the highest available evidence that, in oral cancer, SLNB is as accurate as END in detecting occult lymph node metastases, except for floor-of-mouth tumours.

Indexed as

elective neck dissectionlymphaticslymph node metastasesoral cancersentinel lymph node biopsy

Identifiers

PMID32635357
PMCPMC7407164
OpenAlexW3039315928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.