Evidence map›Paper›PMID 32635293›Full record

ArticleSensors (Basel, Switzerland)2020

A Label-Free Impedimetric Genosensor for the Nucleic Acid Amplification-Free Detection of Extracted RNA of Dengue Virus.

Ching-Chou Wu, Hao-Yu Yen, Lu-Ting Lai, Guey-Chuen Perng, Cheng-Rei Lee, Shuenn-Jue Wu

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ching-Chou WuDepartment of Bio-Industrial Mechatronics Engineering, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung City 402, Taiwan.ORCID 0000-0002-8683-3796
Hao-Yu YenDepartment of Bio-Industrial Mechatronics Engineering, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung City 402, Taiwan.
Lu-Ting LaiDepartment of Bio-Industrial Mechatronics Engineering, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung City 402, Taiwan.
Guey-Chuen PerngDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, No.1, University Rd., Tainan City 701, Taiwan.
Cheng-Rei LeeViral & Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910, USA.
Shuenn-Jue WuViral & Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910, USA.
National Chung Hsing University · TWNaval Medical Research Command · USNational Cheng Kung University · TW

Funding

Henry M. Jackson Foundation Contract No. 895748Ministry of Education in Taiwan Higher Education Sprout ProjectMinistry of Science and Technology of Taiwan MOST107-2313-B-005-006-MY3Naval Medical Research Center Contract No.: N3239818P0305
6 · The paper itself

Abstract

Developing rapid and sensitive diagnostic methods for dengue virus (DENV) infection is of prime priority because DENV infection is the most prevalent mosquito-borne viral disease. This work proposes an electrochemical impedance spectroscopy (EIS)-based genosensor for the label-free and nucleic acid amplification-free detection of extracted DENV RNA intended for a sensitive diagnosis of DENV infection. A concentration ratio of 0.04 mM 6-mercaptohexanoic acid (MHA) to 1 mM 6-mercapto-1-hexanol (MCH) was selected to modify thin-film gold electrodes as a link to control the coverage of self-designed probe DNA (pDNA) at a density of 4.5 ± 0.4 × 10

Indexed as

Biosensing TechniquesDengueDengue VirusDielectric SpectroscopyAnimalsDNA ProbesElectrodesGoldNucleic Acid HybridizationNucleic AcidsRNA, ViralDNA ProbesGoldNucleic AcidsRNA, Viraldengue RNAimpedimetric genosensorlabel-freenucleic acid amplification-freeoverhangprobe DNA density

Identifiers

PMID32635293
PMCPMC7374514
OpenAlexW3039195253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.