Evidence map›Paper›PMID 32635278›Full record

ArticlePathogens (Basel, Switzerland)2020

Inactivation of Scrapie Prions by the Electrically Charged Disinfectant CAC-717.

Akikazu Sakudo, Yoshifumi Iwamaru, Koichi Furusaki, Makoto Haritani, Rumiko Onishi, Morikazu Imamura, Takashi Yokoyama, Yasuhiro Yoshikawa, Takashi Onodera

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akikazu SakudoSchool of Veterinary Medicine, Okayama University of Science, Imabari, Ehime 794-8555, Japan.
Yoshifumi IwamaruNational Institute of Animal Health, Ibaraki 305-1002, Japan.
Koichi FurusakiMineral Activation Research Institute, Kumamoto 865-0023, Japan.
Makoto HaritaniResearch Center for Food Safety, University of Tokyo, Tokyo 113-8657, Japan.
Rumiko OnishiSanta Mineral Co., Ltd., Minato-ku, Tokyo 105-0013, Japan.
Morikazu ImamuraFaculty of Medicine, University of Miyazaki, Kiyotake-cho, Miyazaki 889-1692, Japan.
Takashi YokoyamaNational Institute of Animal Health, Ibaraki 305-1002, Japan.
Yasuhiro YoshikawaSchool of Veterinary Medicine, Okayama University of Science, Imabari, Ehime 794-8555, Japan.
Takashi OnoderaResearch Center for Food Safety, University of Tokyo, Tokyo 113-8657, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have revealed that the electrically charged disinfectant CAC-717 has strong virucidal and bactericidal effects but is safe for humans and animals. In this study, CAC-717 was further evaluated for its potential effects as a disinfectant against scrapie prions. Western blotting showed that CAC-717 reduced the amount of the abnormal isoform of prion protein (PrP

Indexed as

anti-prion compoundcalcium hydrogen carbonatemesoscopic structurescrapie prions

Identifiers

PMID32635278
PMCPMC7400677

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.