Evidence map›Paper›PMID 32635269›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Ensemble Deep Learning for Cervix Image Selection toward Improving Reliability in Automated Cervical Precancer Screening.

Peng Guo, Zhiyun Xue, Zac Mtema, Karen Yeates, Ophira Ginsburg, Maria Demarco, L Rodney Long, Mark Schiffman, Sameer Antani

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Data Characterization for Reliable AI in Medicine.Recent trends in image processing and pattern recognition : 5th International Conference, RTIP2R 2022, Kingsville, TX, USA, December 01-02, 2022, revised selected papers. International Conference on Recent Trends in Image Processing and... · 2023
    Article
  9. Article
  10. Image Quality Classification for Automated Visual Evaluation of Cervical Precancer.Medical image learning with limited and noisy data : first international workshop, MILLanD 2022, held in conjunction with MICCAI 2022, Singapore, September 22, 2022, proceedings. MILLanD (Workshop) (1st : 2022 : Singapore) · 2022
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  15. Deep Metric Learning for Cervical Image Classification.IEEE access : practical innovations, open solutions · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Peng GuoCommunications Engineering Branch, Lister Hill National Center for Biomedical Communications, U.S. National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Zhiyun XueCommunications Engineering Branch, Lister Hill National Center for Biomedical Communications, U.S. National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Zac MtemaIfakara Health Institute, P.O. Box 53 Ifakara, Tanzania.
Karen YeatesDepartment of Medicine, Queen's University, Kingston, ON K7L3N6, Canada.
Ophira GinsburgPerlmutter Cancer Center, NYU Langone Health, New York, NY 10016, USA.
Maria DemarcoDivision of Cancer Epidemiology and Genetics (DCEG), National Cancer Institutes, Bethesda, MD 20892, USA.
L Rodney LongCommunications Engineering Branch, Lister Hill National Center for Biomedical Communications, U.S. National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Mark SchiffmanDivision of Cancer Epidemiology and Genetics (DCEG), National Cancer Institutes, Bethesda, MD 20892, USA.
Sameer AntaniCommunications Engineering Branch, Lister Hill National Center for Biomedical Communications, U.S. National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.

Funding

Image analysis and machine learning for cervical cancer diagnosticsZIALM010014 · NLM · NATIONAL LIBRARY OF MEDICINE · PI ANTANI, SAMEER · 2018 to 2020
$1.7M
6 · The paper itself

Abstract

Automated Visual Examination (AVE) is a deep learning algorithm that aims to improve the effectiveness of cervical precancer screening, particularly in low- and medium-resource regions. It was trained on data from a large longitudinal study conducted by the National Cancer Institute (NCI) and has been shown to accurately identify cervices with early stages of cervical neoplasia for clinical evaluation and treatment. The algorithm processes images of the uterine cervix taken with a digital camera and alerts the user if the woman is a candidate for further evaluation. This requires that the algorithm be presented with images of the cervix, which is the object of interest, of acceptable quality, i.e., in sharp focus, with good illumination, without shadows or other occlusions, and showing the entire squamo-columnar transformation zone. Our prior work has addressed some of these constraints to help discard images that do not meet these criteria. In this work, we present a novel algorithm that determines that the image contains the cervix to a sufficient extent. Non-cervix or other inadequate images could lead to suboptimal or wrong results. Manual removal of such images is labor intensive and time-consuming, particularly in working with large retrospective collections acquired with inadequate quality control. In this work, we present a novel ensemble deep learning method to identify cervix images and non-cervix images in a smartphone-acquired cervical image dataset. The ensemble method combined the assessment of three deep learning architectures, RetinaNet, Deep SVDD, and a customized CNN (Convolutional Neural Network), each using a different strategy to arrive at its decision, i.e., object detection, one-class classification, and binary classification. We examined the performance of each individual architecture and an ensemble of all three architectures. An average accuracy and F-1 score of 91.6% and 0.890, respectively, were achieved on a separate test dataset consisting of more than 30,000 smartphone-captured images.

Indexed as

cervical cancercervix/non-cervixdeep learningensembleone-class classification

Identifiers

PMID32635269
PMCPMC7400120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.