Evidence map›Paper›PMID 32635224›Full record

ArticleCancers2020

Prognostic Value of

Hyun Chang, Yun-Gyoo Lee, Yoon Ho Ko, Jang Ho Cho, Jong-Kwon Choi, Keon Uk Park, Eun Joo Kang, Keun-Wook Lee, Sun Min Lim, Jin-Soo Kim and 6 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03292250 (Public-interest Multicenter Umbrella Trial Based on Genetic Analysis in Korean Head and Neck Cancer and Esophageal Cancer Patient - Part 1), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03292250 phase2completednot on this map

Public-interest Multicenter Umbrella Trial Based on Genetic Analysis in Korean Head and Neck Cancer and Esophageal Cancer Patient - Part 1 (HNSCC)]

TypeinterventionalSponsorSeoul National University HospitalRan2017 to 2022Enrolled180ConditionsHNSCC, Head and Neck NeoplasmsArmsBYL719, Poziotinib, Nintedanib, Abemaciclib, Durvalumab,Tremelimumab
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 13 institutions in 1 country.

Hyun ChangDepartment of Medical Oncology, International St Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon 22711, Korea.
Yun-Gyoo LeeDivision of Hematology and Medical Oncology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, Korea.
Yoon Ho KoDivision of Oncology, Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, Korea.ORCID 0000-0002-2506-3740
Jang Ho ChoDivision of Oncology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon 21431, Korea.
Jong-Kwon ChoiDivision of Hematology and Medical Oncology, Department of Internal Medicine, Konyang University Hospital, Daejeon 35365, Korea.
Keon Uk ParkDivision of Hematology/Oncology, Department of Internal Medicine, Keimyung University Dongsan Hospital, Daegu 51448 Korea.
Eun Joo KangDivision of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Korea.
Keun-Wook LeeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam 13620, Korea.
Sun Min LimDivision of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Yonsei Cancer Center, Seoul 03722, Korea.
Jin-Soo KimDepartment of Internal Medicine, Seoul National University Boramae Medical Center, Seoul 07061, Korea.
Hyun Woo LeeDepartment of Hematology-Oncology, Ajou University School of Medicine, Suwon 16499, Korea.
Min Kyoung KimDivision of Hematology-Oncology, Department of Internal Medicine, Yeungnam University College of Medicine, Daegu 42415, Korea.
In Gyu HwangDivision of Hematology/Oncology, Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul 06973, Korea.
Sangwoo KimDepartment of Biomedical Systems Informatics and Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul 03722, Korea.
Byung-Ho NamHERINGS, The Institute of Advanced Clinical & Biomedical Research, Seoul 08378, Korea.
Hye Ryun KimDivision of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Yonsei Cancer Center, Seoul 03722, Korea.
Yonsei University · KRAjou University · KRCatholic Kwandong University International St. Mary's Hospital · KRCatholic University of Korea · KRChung-Ang University Hospital · KRKangbuk Samsung Hospital · KRKeimyung University · KRKonyang University Hospital · KRKorea University · KRSeoul National University · KRSeoul National University Bundang Hospital · KRThe Catholic University of Korea Incheon St. Mary's Hospital · KRYeungnam University College

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune system dysfunction is associated with head and neck squamous cell carcinoma (HNSCC) development and progression and immune checkpoint inhibitors have demonstrated substantial survival benefits in platinum-refractory HNSCC; therefore, we examined the prognostic value of immune-related gene (IRG) expression in HNSCC. We analyzed the expression of 82 IRGs in 71 patients with HNSCC enrolled in a feasibility study for a prospective HNSCC biomarker-driven umbrella trial (Korean Cancer Study Group TRIUMPH study, NCT03292250).

Indexed as

CD2000R1head and neck cancerimmune cellmRNA expressionprognosis

Identifiers

PMID32635224
PMCPMC7408128
OpenAlexW3040334128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.