Evidence map›Paper›PMID 32635208›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Supplementation of 17β-Estradiol Normalizes Rapid Gastric Emptying by Restoring Impaired Nrf2 and nNOS Function in Obesity-Induced Diabetic Ovariectomized Mice.

Jeremy C Sprouse, Chethan Sampath, Pandu R Gangula

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Depot-specific adiposity changes in ovariectomized mice on high-fat diet.The Journal of veterinary medical science · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jeremy C SprouseSchool of Graduate Studies, Meharry Medical College, Nashville, TN 37208, USA.
Chethan SampathDepartment of ODS & Research, School of Dentistry, Nashville, TN 37208, USA.
Pandu R GangulaDepartment of ODS & Research, School of Dentistry, Nashville, TN 37208, USA.ORCID 0000-0001-7259-570X
University School of Nashville · USMeharry Medical College · US

Funding

The RCMI Program in Health Disparities Research at Meharry Medical College - SupplementU54MD007586 · NIMHD · MEHARRY MEDICAL COLLEGE · PI SANIKA SAMUEL CHIRWA · 2017 to 2026
$48.2M
Technologies and Resources CoreU54MD007593 · NIMHD · MEHARRY MEDICAL COLLEGE · PI ADUNYAH, SAMUEL EVANS · 2012 to 2018
$24.7M
ROLE OF NRF2 IN NITRERGIC MEDIAITED STOMACH MOTILITYSC1GM121282 · NIGMS · MEHARRY MEDICAL COLLEGE · PI GANGULA, PANDU R · 2017 to 2020
$1.4M
NIGMS NIH HHS SC1 GM121282NIGMS NIH HHS SC1GM121282NIMHD NIH HHS U54MD007586NIMHD NIH HHS U54 MD007593
6 · The paper itself

Abstract

Gastroparesis (Gp) is a multifactorial condition commonly observed in females and is characterized by delayed or rapid gastric emptying (GE). The role of ovarian hormones on GE in the pathogenesis of obesity induced type 2 diabetes mellitus (T2DM) is completely unknown. The aims of our study are to investigate whether supplementation of 17β-estradiol (E

Indexed as

antioxidantscytokinesdiabetesestrogengastroparesisnNOSNrf2obesityprogesterone

Identifiers

PMID32635208
PMCPMC7402187
OpenAlexW3039515499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.