ArticleAntioxidants (Basel, Switzerland)2020
Ameliorative Effects of Rhoifolin in Scopolamine-Induced Amnesic Zebrafish (
Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Who cites it
25 citing papers in PubMed, 49 citations in OpenAlex.
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- Integration Viewpoint Using UHPLC-MS/MS, In Silico Analysis, Network Pharmacology, and In Vitro Analysis to Evaluate the Bio-Potential ofMolecules (Basel, Switzerland) · 2025Article
- Rhoifolin as a potential anxiolytic drug for the effects of nicotine withdrawal: beneficial effects on behavior, neuroinflammation, and oxidative stress.Metabolic brain disease · 2025Article
- An Overview of the Natural Neuroprotective Agents for the Management of Cognitive Impairment Induced by Scopolamine in Zebrafish (CNS & neurological disorders drug targets · 2025Review
- Rhoifolin: A promising flavonoid with potent cytotoxic and anticancer properties: molecular mechanisms and therapeutic potential.EXCLI journal · 2025Review
- Rhoifolin Attenuates Concanavalin A-Induced Autoimmune Hepatitis in Mice via JAKs/STATs Mediated Immune and Apoptotic Processes.ACS omega · 2024Article
- The Effect of aPharmaceuticals (Basel, Switzerland) · 2024Article
- Direct Evidence for UsingAntioxidants (Basel, Switzerland) · 2023Article
- In Vitro Antiviral Effect and Potential Neuroprotection ofPharmaceuticals (Basel, Switzerland) · 2023Article
- Promnesic, Anxiolytic and Antioxidant Effects ofPlants (Basel, Switzerland) · 2023Article
- Chemical characterization and metabolic profiling of Xiao-Er-An-Shen Decoction by UPLC-QTOF/MS.Frontiers in pharmacology · 2023Article
- Zebrafish: A Pharmacological Model for Learning and Memory Research.Molecules (Basel, Switzerland) · 2022Review
- Neuroprotective Effect ofMolecules (Basel, Switzerland) · 2022Article
- The potential mechanism of Bupleurum against anxiety was predicted by network pharmacology study and molecular docking.Metabolic brain disease · 2022Article
- Neuroprotective Potential ofPlants (Basel, Switzerland) · 2022Article
- GC/MS Profiling, Anti-Collagenase, Anti-Elastase, Anti-Tyrosinase and Anti-Hyaluronidase Activities of aPlants (Basel, Switzerland) · 2022Article
- Wound-Healing Potential of Rhoifolin-Rich Fraction Isolated fromPharmaceuticals (Basel, Switzerland) · 2022Article
- In Vitro and In Vivo Studies of Anti-Lung Cancer Activity ofAntioxidants (Basel, Switzerland) · 2021Article
- Article
- Baicalein 5,6-Dimethyl Ether Prevents Memory Deficits in the Scopolamine Zebrafish Model by Regulating Cholinergic and Antioxidant Systems.Plants (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
Rhoifolin (Rho) exerts many biological activities such as anticancer, antidiabetic, hepatoprotective, antirheumatic, antibacterial, and antiviral properties. The neuroprotective action of this compound has not been studied. The goal of this study was to investigate the improvement impact of Rho on scopolamine (Sco)-induced zebrafish anxiety, amnesia, and brain oxidative stress and to elucidate the underlying mechanisms involved. Zebrafish were treated with Rho (1, 3, and 5 μg/L) for nine consecutive days and were subsequently subjected to Sco (100 μM) 30 min before behavioral tests (novel tank diving test, Y-maze, and novel object recognition tests). Rho was isolated from
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.