GuidelinePediatric research2020
COVID-19 PICU guidelines: for high- and limited-resource settings.
Guideline in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 5 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- High-flow nasal cannula for lower respiratory infections in children under 2 years: a systematic review of indications.Archives of disease in childhood · 2026Pooled it
- Seizures in children undergoing extracorporeal membrane oxygenation: a systematic review and meta-analysis.Pediatric research · 2023Pooled it
- International alliance and AGREE-ment of 71 clinical practice guidelines on the management of critical care patients with COVID-19: a living systematic review.Journal of clinical epidemiology · 2022Pooled it
- Multisystem inflammatory syndrome in children: a microcosm of challenges and opportunities for translational bioinformatics in pediatric research.Current opinion in pediatrics · 2021Pooled it
- COVID-19 FAQs in paediatric and congenital cardiology: AEPC position paper.Cardiology in the young · 2021Guideline
- Minimizing Societal Cost of Epidemics: Optimal Catastrophe Insurance Compensation Allocation.Risk analysis : an official publication of the Society for Risk Analysis · 2026Article
- Assessment of the development of social skills among undergraduate medical students through participation in a socio-educational project during the coronavirus disease (COVID)-19 pandemic: a Brazilian pilot study.BMC medical education · 2024Observational
- Intestinal parasitic infections in children from marginalised Roma communities: prevalence and risk factors.BMC infectious diseases · 2024Article
- Treatment of multisystem inflammatory syndrome in children.World journal of pediatrics : WJP · 2024Review
- Airway Management of Critically Ill Pediatric Patients with Suspected or Proven Coronavirus Disease 2019 Infection: An Intensivist Point of View.Journal of pediatric intensive care · 2024Review
- Observational
- The change of the COVID-19 pandemic on medical education in Korea: a national survey of medical schools.Korean journal of medical education · 2023Article
- Respiratory Care in Children with COVID-19.Journal of pediatric intensive care · 2023Review
- COVID-19-Associated Paediatric Inflammatory Multisystem Syndrome (PIMS-TS) in Intensive Care: A Retrospective Cohort Trial (PIMS-TS INT).Children (Basel, Switzerland) · 2023Article
- Medications and Adherence to Treatment Guidelines Among Children Hospitalized With Acute COVID-19.Pediatrics · 2022Article
- COVID-19 in Children.Pediatric clinics of North America · 2022Review
- Organisation of care in paediatric intensive care units during the first 18 months of the COVID-19 pandemic: a scoping review protocol.BMJ open · 2022Article
- Comparative Clinical Characteristics, Laboratory Findings, and Outcomes of Hypoxemic and Non-Hypoxemic Patients Treated at a Makeshift COVID-19 Unit in Bangladesh: A Retrospective Chart Analysis.Journal of clinical medicine · 2022Article
- Critically Ill Pediatric Patient and SARS-CoV-2 Infection.Children (Basel, Switzerland) · 2022Review
- Investigations into the efficacy of a novel extubation-aerosol shield: a cough model study.Infection prevention in practice · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 14 institutions in 11 countries.
Funding
Abstract
backgroundFewer children than adults have been affected by the COVID-19 pandemic, and the clinical manifestations are distinct from those of adults. Some children particularly those with acute or chronic co-morbidities are likely to develop critical illness. Recently, a multisystem inflammatory syndrome (MIS-C) has been described in children with some of these patients requiring care in the pediatric ICU.
methodsAn international collaboration was formed to review the available evidence and develop evidence-based guidelines for the care of critically ill children with SARS-CoV-2 infection. Where the evidence was lacking, those gaps were replaced with consensus-based guidelines.
resultsThis process has generated 44 recommendations related to pediatric COVID-19 patients presenting with respiratory distress or failure, sepsis or septic shock, cardiopulmonary arrest, MIS-C, those requiring adjuvant therapies, or ECMO. Evidence to explain the milder disease patterns in children and the potential to use repurposed anti-viral drugs, anti-inflammatory or anti-thrombotic therapies are also described.
conclusionBrief summaries of pediatric SARS-CoV-2 infection in different regions of the world are included since few registries are capturing this data globally. These guidelines seek to harmonize the standards and strategies for intensive care that critically ill children with COVID-19 receive across the world. IMPACT: At the time of publication, this is the latest evidence for managing critically ill children infected with SARS-CoV-2. Referring to these guidelines can decrease the morbidity and potentially the mortality of children effected by COVID-19 and its sequalae. These guidelines can be adapted to both high- and limited-resource settings.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.