Evidence map›Paper›PMID 32634596›Full record

ArticleNeuroImage2020

Personalized connectome fingerprints: Their importance in cognition from childhood to adult years.

B C Munsell, E Gleichgerrcht, E Hofesmann, J Delgaizo, C R McDonald, B Marebwa, M A Styner, J Fridriksson, C Rorden, N K Focke and 2 more

Open access · goldAbstract read
In one paragraph

Article in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

B C MunsellUniversity of North Carolina, Department of Psychiatry, USA; University of North Carolina, Department of Computer Science, USA. Electronic address: brent_munsell@med.unc.edu.
E GleichgerrchtMedical University of South Carolina, Department of Neurology, USA.
E HofesmannUniversity of Michigan, Department of Electrical Engineering and Computer Science, USA.
J DelgaizoMedical University of South Carolina, Department of Neurology, USA.
C R McDonaldUniversity of California San Diego, Department of Psychiatry, USA.
B MarebwaMedical University of South Carolina, Department of Neurology, USA.
M A StynerUniversity of North Carolina, Department of Psychiatry, USA; University of North Carolina, Department of Computer Science, USA.
J FridrikssonUniversity of South Carolina, Department of Communication Sciences & Disorders, USA.
C RordenUniversity of South Carolina, Department of Psychology, USA.
N K FockeUniversity of Göttingen, Department of Clinical Neurophysiology, Germany.
J H GilmoreUniversity of North Carolina, Department of Psychiatry, USA.
L BonilhaMedical University of South Carolina, Department of Neurology, USA.
Medical University of South Carolina · USUniversity of South Carolina · USUniversity of California, San Diego · USUniversity of Göttingen · DEUniversity of Michigan–Ann Arbor · US

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HICKOK, GREGORY · 2016 to 2025
$25.0M
National Neuropsychological Network (NNN)R01MH118514 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DANIEL L DRANE, David W. Loring · 2019 to 2026
$9.4M
Cortical and Subcortical Organization of Language-Related Semantic Processing in Alzheimer's DiseaseR01DC014021 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BONILHA, LEONARDO F · 2014 to 2023
$4.7M
Early Brain Development in One and Two Year OldsR01HD053000 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GILMORE, JOHN HORACE · 2007 to 2018
$4.4M
Predicting Epilepsy Surgery Outcomes Using Neural Network ArchitectureR01NS110347 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BONILHA, LEONARDO F, DRANE, DANIEL L · 2019 to 2023
$3.6M
Prediction of seizure lateralization and postoperative outcome through the use of deep learning applied to multi-site MRI/DTI data: An ENIGMA-Epilepsy studyR21NS107739 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BONILHA, LEONARDO F, MCDONALD, CARRIE R · 2019 to 2019
$444k
NICHD NIH HHS R01 HD053000NIDCD NIH HHS P50 DC014664NIDCD NIH HHS R01 DC014021NIMH NIH HHS R01 MH118514NINDS NIH HHS R01 NS110347NINDS NIH HHS R21 NS107739
6 · The paper itself

Abstract

Structural neural network architecture patterns in the human brain could be related to individual differences in phenotype, behavior, genetic determinants, and clinical outcomes from neuropsychiatric disorders. Recent studies have indicated that a personalized neural (brain) fingerprint can be identified from structural brain connectomes. However, the accuracy, reproducibility and translational potential of personalized fingerprints in terms of cognition is not yet fully determined. In this study, we introduce a dynamic connectome modeling approach to identify a critical set of white matter subnetworks that can be used as a personalized fingerprint. Several individual variable assessments were performed that demonstrate the accuracy and practicality of personalized fingerprint, specifically predicting the identity and IQ of middle age adults, and the developmental quotient in toddlers. Our findings suggest the fingerprint found by our dynamic modeling approach is sufficient for differentiation between individuals, and is also capable of predicting general intellectual ability across human development.

Indexed as

Machine LearningNeuroimagingAdultAgedChild, PreschoolCognitionFemaleHuman DevelopmentHumansInfantIntelligenceLearningMagnetic Resonance ImagingMaleMiddle AgedNerve NetConnectome fingerprintingDevelopmental neuroscienceNetwork analysisNeurological identity and functionStructural connectivity

Identifiers

PMID32634596
PMCPMC11316952
OpenAlexW3038174193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.