Evidence map›Paper›PMID 32634193›Full record

ArticleCell medicine2019

Mitochondrial Respiratory Capacity is Restored in Hibernating Cardiomyocytes Following Co-Culture with Mesenchymal Stem Cells.

Laura L Hocum Stone, Erin Chappuis, Maribel Marquez, Edward O McFalls, Rosemary F Kelly, Tammy Butterick

Open access · hybridAbstract read
In one paragraph

Article in Cell medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Laura L Hocum StoneResearch Service, Minneapolis VA Health Care System, USA.
Erin ChappuisResearch Service, Minneapolis VA Health Care System, USA.
Maribel MarquezDepartment of Physiology, Cardiovascular Center, Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, USA.
Edward O McFallsResearch Service, Minneapolis VA Health Care System, USA.
Rosemary F KellyResearch Service, Minneapolis VA Health Care System, USA.
Tammy ButterickResearch Service, Minneapolis VA Health Care System, USA.
Minneapolis VA Health Care System · USMedical College of Wisconsin · US

Funding

BLRD VA I01 BX000760BLRD VA I01 BX004146BLRD VA IK2 BX001686BLRD VA IS1 BX003083BLRD VA IS1 BX003578BLRD VA IS1 BX003579
6 · The paper itself

Abstract

Hibernating myocardium is a subset of ischemic cardiac disease characterized by viable but dysfunctional tissue. Standard treatment for hibernating myocardium is coronary artery bypass graft, which reduces arrhythmias and improves survival but does not fully restore function, presenting a gap in currently available treatments. Large animal studies of hibernating myocardium have identified impaired mitochondrial dynamics as a root cause of persistent cardiac dysfunction despite surgical revascularization. This study presents a novel

Indexed as

Hibernating myocardiummesenchymal stem cellsmitochondrial respirationperoxisome proliferator-activated receptor gamma coactivator 1-alpha

Identifiers

PMID32634193
PMCPMC6404044
OpenAlexW2922334187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.