Evidence map›Paper›PMID 32634117›Full record

ReviewAging2020

Healthspan pathway maps in

Steffen Möller, Nadine Saul, Alan A Cohen, Rüdiger Köhling, Sina Sender, Hugo Murua Escobar, Christian Junghanss, Francesca Cirulli, Alessandra Berry, Peter Antal and 13 more

Open access · greenAbstract readReview
In one paragraph

Review in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. PMFrontiers in public health · 2023
    Article
  3. Article
  4. Review
  5. Article
  6. Knock-down ofAging · 2021
    Article
  7. Genes implicated inBiology letters · 2021
    Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 10 institutions in 7 countries.

Steffen MöllerRostock University Medical Center, Institute for Biostatistics and Informatics in Medicine and Aging Research, IBIMA, Rostock, Germany.
Nadine SaulHumboldt-University of Berlin, Institute of Biology, Berlin, Germany.
Alan A CohenDepartment of Family Medicine, University of Sherbrooke, Sherbrooke, Canada.
Rüdiger KöhlingRostock University Medical Center, Oscar-Langendorff-Institute for Physiology, Rostock, Germany.
Sina SenderRostock University Medical Center, Department of Hematology, Oncology and Palliative Medicine, Rostock, Germany.
Hugo Murua EscobarRostock University Medical Center, Department of Hematology, Oncology and Palliative Medicine, Rostock, Germany.
Christian JunghanssRostock University Medical Center, Department of Hematology, Oncology and Palliative Medicine, Rostock, Germany.
Francesca CirulliCenter for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy.
Alessandra BerryCenter for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità, Rome, Italy.
Peter AntalDepartment of Measurement and Information Systems, Budapest University of Technology and Economics, Budapest, Hungary.
Priit AdlerInstitute of Computer Science, BIIT research group, University of Tartu, Tartu, Estonia.
Jaak ViloInstitute of Computer Science, BIIT research group, University of Tartu, Tartu, Estonia.
Michele BoianiMax-Planck Institute for Molecular Biomedicine, Münster, Germany.
Ludger JansenUniversity of Rostock, Institute for Philosophy, Rostock, Germany.
Dirk RepsilberSchool of Medical Sciences, University of School of Medical Sciences, University of Örebro, School of Medical Sciences, University of Örebro, Örebro, Sweden.
Hans Jörgen GrabeUniversity Medicine Greifswald, Clinic and Polyclinic for Psychiatry and Psychotherapy, Greifswald, Germany.
Stephan StruckmannRostock University Medical Center, Institute for Biostatistics and Informatics in Medicine and Aging Research, IBIMA, Rostock, Germany.
Israel BarrantesRostock University Medical Center, Institute for Biostatistics and Informatics in Medicine and Aging Research, IBIMA, Rostock, Germany.
Mohamed HamedRostock University Medical Center, Institute for Biostatistics and Informatics in Medicine and Aging Research, IBIMA, Rostock, Germany.
Brecht WoutersKU Leuven, Department of Biology, Leuven, Belgium.
Liliane SchoofsKU Leuven, Department of Biology, Leuven, Belgium.
Walter LuytenKU Leuven, Department of Biology, Leuven, Belgium.
Georg FuellenRostock University Medical Center, Institute for Biostatistics and Informatics in Medicine and Aging Research, IBIMA, Rostock, Germany.
University of Rostock · DEKU Leuven · BEIstituto Superiore di Sanità · ITUniversitätsmedizin Greifswald · DEUniversity of Tartu · EEBudapest University of Technology and Economics · HUHumboldt-Universität zu Berlin · DEMax Planck Institute for Molecular Biomedicine · DEÖrebro University · SEUniversité de Sherbrooke · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular basis of aging and of aging-associated diseases is being unraveled at an increasing pace. An extended healthspan, and not merely an extension of lifespan, has become the aim of medical practice. Here, we define health based on the absence of diseases and dysfunctions. Based on an extensive review of the literature, in particular for humans and

Indexed as

AgingProtein Interaction MapsAnimalsCaenorhabditis elegansCell ProliferationHumansLipid MetabolismLipidsLongevityReceptors, NotchSignal TransductionLipidsReceptors, Notchgene expression analysisnetwork biology analysis

Identifiers

PMID32634117
PMCPMC7377848
OpenAlexW3041720207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.