ArticleAmerican journal of respiratory and critical care medicine2020
Long Noncoding RNA TYKRIL Plays a Role in Pulmonary Hypertension via the p53-mediated Regulation of PDGFRβ.
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Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 2% of its field
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.
- Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension.Science translational medicine · 2024Pooled it
- Hypoxic microenvironment and pulmonary hypertension.Respiratory research · 2025Review
- Living human lung slices for ex vivo modelling of lung cancer.JCI insight · 2025Article
- LncRNA-536 and RNA-Binding Protein RBM25 Interactions in Pulmonary Artery Smooth Muscle Cells: Implications in Pulmonary Hypertension.Arteriosclerosis, thrombosis, and vascular biology · 2025Article
- Therapeutic targets for pulmonary arterial hypertension: insights into the emerging landscape.Expert opinion on therapeutic targets · 2025Review
- Review
- Unraveling AURKB as a potential therapeutic target in pulmonary hypertension using integrated transcriptomic analysis and pre-clinical studies.Cell reports. Medicine · 2025Article
- Deciphering the Complexities of Pulmonary Hypertension: The Emergent Role of Single-Cell Omics.American journal of respiratory cell and molecular biology · 2025Review
- Pathology and pathobiology of pulmonary hypertension: current insights and future directions.The European respiratory journal · 2024Review
- Current Overview of the Biology and Pharmacology in Sugen/Hypoxia-Induced Pulmonary Hypertension in Rats.Journal of aerosol medicine and pulmonary drug delivery · 2024Review
- Pulmonary artery smooth muscle cell pyroptosis promotes the proliferation of PASMCs by paracrine IL‑1β and IL‑18 in monocrotaline‑induced pulmonary arterial hypertensive rats.Experimental and therapeutic medicine · 2024Article
- A HIF-2α-dependentAnnals of translational medicine · 2024Article
- Roles of LncRNAs in the Pathogenesis of Pulmonary Hypertension.Reviews in cardiovascular medicine · 2024Review
- Precision cut lung slices: an integrated ex vivo model for studying lung physiology, pharmacology, disease pathogenesis and drug discovery.Respiratory research · 2024Review
- Emerging Epigenetic Targets and Their Molecular Impact on Vascular Remodeling in Pulmonary Hypertension.Cells · 2024Review
- p53-regulated lncRNAs in cancers: from proliferation and metastasis to therapy.Cancer gene therapy · 2023Review
- Pulmonary Hypertension: A Contemporary Review.American journal of respiratory and critical care medicine · 2023Review
- Pharmacology and Rationale for Seralutinib in the Treatment of Pulmonary Arterial Hypertension.International journal of molecular sciences · 2023Review
- Novel lncRNA LNC_000113 Drives the Activation of Pulmonary Adventitial Fibroblasts through Modulating PTEN/Akt/FoxO1 Pathway.Journal of cardiovascular development and disease · 2023Article
- Single Nucleotide Polymorphism rs9277336 Controls the Nuclear Alpha Actinin 4-Human Leukocyte Antigen-DPA1 Axis and Pulmonary Endothelial Pathophenotypes in Pulmonary Arterial Hypertension.Journal of the American Heart Association · 2023Article
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Authors and funding
23 authors at 7 institutions in 3 countries.
Christoph M ZehendnerInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
Chanil ValasarajanDepartment of Lung Development and Remodeling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Bad Nauheim, Germany.
Astrid WernerInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
Jes-Niels BoeckelInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
Florian C BischoffInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
David JohnInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
Tyler WeirickInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
Simone F GlaserInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
Oliver RossbachDepartment of Biology and Chemistry, Institute of Biochemistry, University of Giessen, Giessen, Germany.
Nicolas JaéInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
Shemsi DemolliInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
Fatemeh KhassafiDepartment of Lung Development and Remodeling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Bad Nauheim, Germany.
Ke YuanDivision of Pulmonary and Critical Care Medicine, Stanford University, Stanford, California.
Vinicio A de Jesus PerezDivision of Pulmonary and Critical Care Medicine, Stanford University, Stanford, California.
Katharina M MichalikInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
Wei ChenLaboratory for Novel Sequencing Technology, Functional and Medical Genomics, Berlin Institute for Medical Systems Biology, Max-Delbruck-Centre for Molecular Medicine, Berlin, Germany.
Werner SeegerDepartment of Lung Development and Remodeling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Bad Nauheim, Germany.
Andreas GuentherDepartment of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC), member of the DZL, Justus Liebig University, Giessen, Germany.
Roxana M WasnickDepartment of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC), member of the DZL, Justus Liebig University, Giessen, Germany.
Shizuka UchidaInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
Andreas M ZeiherZIM III, Department of Cardiology, Goethe University, Frankfurt am Main, Germany.
Stefanie DimmelerInstitute for Cardiovascular Regeneration, Centre for Molecular Medicine, and.
Soni S PullamsettiDepartment of Lung Development and Remodeling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Bad Nauheim, Germany.ORCID 0000-0003-0440-8831
Justus-Liebig-Universität Gießen · DEGerman Centre for Cardiovascular Research · DEGoethe University Frankfurt · DEMax Planck Institute for Heart and Lung Research · DEStanford University · USUniversity of Louisville · USMax Delbrück Center · DE
Funding
The Wnt7a/ROR2 axis in the pathogenesis of pulmonary arterial hypertensionR01HL134776 · NHLBI · STANFORD UNIVERSITY · PI DE JESUS PEREZ, VINICIO A · 2017 to 2025
$5.0MEndothelial-pericyte interactions in the pathogenesis of pulmonary arterial hypertensionR01HL139664 · NHLBI · STANFORD UNIVERSITY · PI DE JESUS PEREZ, VINICIO A · 2018 to 2025
$4.7MNHLBI NIH HHS R01 HL134776NHLBI NIH HHS R01 HL139664
Abstract
PubMed holds no abstract for this paper.
Indexed as
Gene ExpressionRNA, Long NoncodingAdultAgedAged, 80 and overFemaleHumansHypertension, PulmonaryMaleMiddle AgedProtein-Tyrosine KinasesReceptor, Platelet-Derived Growth Factor betaSignal TransductionProtein-Tyrosine KinasesReceptor, Platelet-Derived Growth Factor betaRNA, Long Noncodinghuman precision-cut lung sliceslong noncoding RNAsplatelet-derived growth factor receptor βsmooth muscle cellsvascular remodeling
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LicenceCC BY-NC-ND
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.