ReviewAfrican journal of primary health care & family medicine2020
General side effects and challenges associated with anti-epilepsy medication: A review of related literature.
Review in African journal of primary health care & family medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Parent perceptions and decision making about treatments for epilepsy: a qualitative evidence synthesis.BMJ open · 2023Pooled it
- Chinese Herbal Medicine Combined With Antiepileptic Drugs for Intractable Epilepsy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Frontiers in pharmacology · 2022Pooled it
- Medical Technology: A Systematic Review on Medical Devices Utilized for Epilepsy Prediction and Management.Current neuropharmacology · 2022Pooled it
- Article
- Burden and Determinants of Adverse Effects from Antiseizure Medications: Insights from Saudi Cohort.Medicina (Kaunas, Lithuania) · 2026Article
- Genetic medicines for epilepsy: unlocking new avenues for seizure control.Frontiers in bioengineering and biotechnology · 2026Review
- A description of feeding and swallowing in neonates with hypoxic ischemic encephalopathy.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2025Article
- Upregulation of CCK3R leading to the suppression of chronic seizures.Translational psychiatry · 2025Article
- Revolutionizing Huntington's Disease Treatment: Breakthroughs in AAV-Mediated Gene Therapy.Cells · 2025Review
- Optimization of seizure prevention by cannabidiol (CBD).Translational neuroscience · 2025Article
- Dual strategies for epilepsy management employing pharmacological and non-invasive brain stimulation approaches.Frontiers in neurology · 2025Review
- Neurostimulation for the Management of Epilepsy: Advances in Targeted Therapy.Current drug targets · 2025Review
- Preventive effects of transcranial photobiomodulation on epileptogenesis in a kainic acid-induced rat epilepsy model.Experimental neurology · 2025Article
- Vitamin D Relieves Epilepsy Symptoms and Neuroinflammation in Juvenile Mice by Activating the mTOR Signaling Pathway via RAF1: Insights from Network Pharmacology and Molecular Docking Studies.Neurochemical research · 2024Article
- Characterizing psychopharmacological prescribing practices in a large cohort of adolescents with borderline personality disorder.Borderline personality disorder and emotion dysregulation · 2024Article
- Epilepsy in rural South Africa: Patient experiences and healthcare challenges.Epilepsia open · 2024Article
- The Role of Pharmacists' Interventions in Increasing Medication Adherence of Patients With Epilepsy: A Scoping Review.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024Article
- Review
- Inhibition of Seizure-Like Paroxysms and Toxicity Effects ofACS chemical neuroscience · 2024Article
- Effects of physical activity on cognition and psychosocial functioning in pediatric epilepsy: A systematic review.Epilepsy & behavior reports · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study is coming against the background of people with epilepsy who are abandoning anti-epilepsy medication in developing countries, such as Zimbabwe.
aimThe aim of this article was therefore to review the general side effects and challenges associated with these anti-epilepsy medications.
settingThe researchers reviewed literature related to the general side effects, psychological, social and economic challenges associated with anti- epilepsy medication.
methodsTo answer the research questions, the researchers used a narrative approach.
resultsFindings of the study reflected that the general side effects associated with anti- epilepsy medication include feelings of tiredness, stomach upset, dizziness or blurred vision, which usually happen during the first weeks of taking medicines. Psychologically, an individual with epilepsy may suffer cognitive problems that are associated with thinking, remembering, paying attention or concentrating and finding the right words to use. Socially, people with epilepsy experience social isolation, dependent behaviour, low rates of marriages, unemployment and reduced quality of life. Using anti-epilepsy medication is also associated with economic challenges.
conclusionThe researchers concluded that some people with epilepsy have discontinued using anti-epilepsy medications because of these side effects and challenges.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.