Observational studyInternational wound journal2020
Multidrug resistant organism predicts ulcer recurrence following surgical management of diabetic foot osteomyelitis.
Observational study in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 24 citations in OpenAlex.
- Risk Factors Associated With Multidrug Resistant Organism (MDRO) Isolates in Infected Diabetic Foot Ulcers (DFU): An Analytical Cross-sectional Study.Journal of the ASEAN Federation of Endocrine Societies · 2026Article
- Adjuvant local antibiotic therapy in the management of diabetic foot osteomyelitis.Clinical diabetes and endocrinology · 2024Article
- Level of 25-hydroxyvitamin D and vitamin D receptor in diabetic foot ulcer and factor associated with diabetic foot ulcers.Diabetology & metabolic syndrome · 2023Article
- Bacterial Diversity and Antibiotic Resistance in Patients with Diabetic Foot Osteomyelitis.Antibiotics (Basel, Switzerland) · 2023Article
- On diabetic foot ulcer knowledge gaps, innovation, evaluation, prediction markers, and clinical needs.Journal of diabetes and its complications · 2022Review
- Metagenomics to Identify Pathogens in Diabetic Foot Ulcers and the Potential Impact for Clinical Care.Current diabetes reports · 2021Review
- Multidrug resistant organism predicts ulcer recurrence following surgical management of diabetic foot osteomyelitis.International wound journal · 2020Observational
- Diabetic foot infection severity as a predictor of re-ulceration following partial forefoot amputation.The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Diabetic foot ulcers commonly precede diabetic foot osteomyelitis (DFO) and once the latter occurs, surgical management is often performed. The presence of osteomyelitis is an independent risk factor for the development of re-ulceration. We investigated the relationship between causative organisms in osteomyelitis and 1-year diabetic foot outcomes (re-ulceration, amputation, and death) following surgical management in an observational cohort of 223 patients. Univariate and multivariate analyses were performed for available demographic, clinical, and laboratory data. In addition, random forest plots were used to identify microbiologic predictors of 1-year outcomes. Patients with osteomyelitis managed surgically were younger and exhibited more painful peripheral neuropathy than outpatients with diabetes alone (both P < .0001). Osteomyelitis proximal margin cultures were diverse, at times polymicrobial, and included multidrug-resistant organisms in 13.9% of the cohort. In patients who underwent surgery, 44.5% experienced a re-ulceration on the same foot within 12 months of surgery. The presence of multidrug-resistant organisms on proximal bone culture was found to be a significant predictor of diabetic foot ulcer recurrence in univariate modelling (P < .001) and importance rankings. This is the first study to use prediction modelling to identify a relationship between multidrug-resistant organisms and diabetic foot ulcer recurrence following DFO.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.