ArticleJournal of medical virology2021
The "scar" of a pandemic: Cumulative incidence of COVID-19 during the first trimester of pregnancy.
Article in Journal of medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Pooled it
- Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis.Proceedings of the National Academy of Sciences of the United States of America · 2021Pooled it
- The seroprevalence of SARS-CoV-2 during the first wave in Europe 2020: A systematic review.PloS one · 2021Pooled it
- Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis.BMJ (Clinical research ed.) · 2020Pooled it
- Longitudinal analysis of antibody response following SARS-CoV-2 infection in pregnancy: From the first trimester to delivery.Journal of reproductive immunology · 2021Trial
- COVID-19 incidence in women of reproductive age: a population-based study in Reggio Emilia, northern Italy.BMC pregnancy and childbirth · 2023Article
- Shadow of a Pandemic: Persistence of Prenatal SARS-CoV-2 Antibodies in Newborn Blood Spots.International journal of neonatal screening · 2023Article
- Vlogging Pregnancy and Laboring During the Pandemic on YouTube.The Journal of perinatal education · 2023Article
- Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection.Brain : a journal of neurology · 2023Article
- Monitoring SARS-CoV-2 seroprevalence over time among pregnant women admitted to delivery units: Suitability for surveillance.PloS one · 2023Article
- COVID-19 and pregnancy: clinical outcomes; mechanisms, and vaccine efficacy.Translational research : the journal of laboratory and clinical medicine · 2023Review
- Cardiovascular Complications of COVID-19 among Pregnant Women and Their Fetuses: A Systematic Review.Journal of clinical medicine · 2022Review
- A temporal study of Brazilian pregnant and postpartum women vulnerability for COVID-19: Characteristics, risk factors and outcomes.Lancet regional health. Americas · 2022Article
- Impact of COVID-19 on pregnant women in South Korea: Focusing on prevalence, severity, and clinical outcomes.Journal of infection and public health · 2022Article
- Obstetric and neonatal outcomes after SARS-CoV-2 infection in the first trimester of pregnancy: A prospective comparative study.The journal of obstetrics and gynaecology research · 2022Observational
- The COVID-19 Pandemic Impact on the Outcome of Medically Assisted Reproduction Pregnancies.Frontiers in reproductive health · 2022Article
- First-Trimester SARS-CoV-2 Infection: Clinical Presentation, Inflammatory Markers, and Obstetric Outcomes.Fetal diagnosis and therapy · 2022Article
- Article
- Seroprevalence of anti-SARS-CoV-2 antibodies in women attending antenatal care in eastern Ethiopia: a facility-based surveillance.BMJ open · 2021Article
- Placenta histopathology in SARS-CoV-2 infection: analysis of a consecutive series and comparison with control cohorts.Virchows Archiv : an international journal of pathology · 2021Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenitally- or perinatally-acquired viral infections can be harmful to the fetus but data are limited about prevalence and outcomes of coronavirus disease 2019 (COVID-19) disease during the first trimester of pregnancy. We report epidemiologic data from a study investigating a cohort of women who became pregnant just before or during the COVID-19 pandemic. We recruited 138 consecutive pregnant women attending for first trimester screening (11-13 weeks of gestation) at Sant'Anna Hospital, Turin, Piedmont, Italy, during the plateau and the falling phase of the COVID-19 epidemic curve. Patients were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin M/immunoglobulin G antibody levels and SARS-CoV-2 detection in sera and nasopharyngeal swab samples. COVID-19 cumulative incidence during the first trimester was of 10.1% with high prevalence of asymptomatic patients (42.8%). Similar to the course of the disease in non pregnant adults, 80% to 90% of infections were not severe.The prevalence of reported symptoms was four-fold higher in SARS-CoV-2 positive patients (57%) than in those negative (13%) (P < .001), suggesting that direct self-testing should open doors to confirmatory testing for COVID-19. Our findings support the need for COVID-19 screening in early pregnancy in epidemic areas to plan materno-fetal health surveillance programs.
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