ArticleJournal of the American Geriatrics Society2020
Identification of Sarcopenia Components That Discriminate Slow Walking Speed: A Pooled Data Analysis.
Article in Journal of the American Geriatrics Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- BIO101 in Sarcopenic Seniors at Risk of Mobility Disability: Results of a Double-Blind Randomised Interventional Phase 2b Trial.Journal of cachexia, sarcopenia and muscle · 2025Trial
- Age-related increase in the excitability of mouse layer V pyramidal neurons in the primary motor cortex is accompanied by an increased persistent inward current.GeroScience · 2025Article
- Health outcomes of sarcopenia: a consensus report by the outcome working group of the Global Leadership Initiative in Sarcopenia (GLIS).Aging clinical and experimental research · 2025Review
- How does the cut-off point for grip strength affect the prevalence of sarcopenia and associated factors? Findings from the ELSI-Brazil Study.Cadernos de saude publica · 2025Article
- Can EWGSOP2 and SDOC Definitions of Sarcopenia Identify Functional Muscle Quality?Journal of frailty, sarcopenia and falls · 2024Article
- Supervised Machine Learning to Examine Factors Associated with Respiratory Sinus Arrhythmias and Ectopic Heart Beats in Adults: A Pilot Study.Hearts (Basel, Switzerland) · 2024Article
- Collective Weakness and Fluidity in Weakness Status Associated With Basic Self-Care Limitations in Older Americans.American journal of medicine open · 2024Article
- Weakness Thresholds Are Differentially Linked to Cognitive Function by Obesity Status in Older Americans.Journal of Alzheimer's disease reports · 2024Article
- Weakness Status is Differentially Associated with Time to Diabetes in Americans.Advances in geriatric medicine and research · 2024Article
- A Critical Review of Current Worldwide Definitions of Sarcopenia.Calcified tissue international · 2024Review
- The Role of Different Weakness Cut-Points for Future Cognitive Impairment in Older Americans.Journal of the American Medical Directors Association · 2023Article
- Predicting Slow Walking Speed From a Pooled Cohort Analysis: Sarcopenia Definitions, Agreement, and Prevalence in Australia and New Zealand.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Examining the role of different weakness categories for mobility and future falls in older Americans.Aging clinical and experimental research · 2023Article
- Spot Urinary Creatinine Concentration in Patients with Chronic Heart Failure Identifies a Distinct Muscle-Wasting Phenotype with a Strikingly Different Risk of Mortality.Biomedicines · 2023Article
- Grip strength cut-points from the Swiss DO-HEALTH population.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2023Article
- Optimizing the Design of Clinical Trials to Evaluate the Efficacy of Function-Promoting Therapies.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Sarcopenia Definition Outcome Consortium - defined Weakness and Risk of Falls: The National Health and Aging Trends Survey.Geriatrics & gerontology international · 2023Article
- Hand Grip Strength Relative to Waist Circumference as a Means to Identify Men and Women Possessing Intact Mobility in a Cohort of Older Adults with Type 2 Diabetes.Biomedicines · 2023Article
- Associations between biomarkers of cellular senescence and physical function in humans: observations from the lifestyle interventions for elders (LIFE) study.GeroScience · 2022Article
- Public Health Need, Molecular Targets, and Opportunities for the Accelerated Development of Function-Promoting Therapies: Proceedings of a National Institute on Aging Workshop.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
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23 authors.
Funding
Abstract
backgroundThe Sarcopenia Definitions and Outcomes Consortium (SDOC) sought to identify cut points for muscle strength and body composition measures derived from dual-energy x-ray absorptiometry (DXA) that discriminate older adults with slow walking speed. This article presents the core analyses used to guide the SDOC position statements.
designCross-sectional data analyses of pooled data.
settingUniversity-based research assessment centers.
participantsCommunity-dwelling men (n = 13,652) and women: (n = 5,115) with information on lean mass by DXA, grip strength (GR), and walking speed. MEASUREMENTS: Thirty-five candidate sarcopenia variables were entered into sex-stratified classification and regression tree (CART) models to agnostically choose variables and cut points that discriminate slow walkers (<0.80 m/s). Models with alternative walking speed outcomes were also evaluated (<0.60 and <1.0 m/s and walking speed treated continuously).
resultsCART models identified GR/body mass index (GRBMI) and GR/total body fat (GRTBF) as the primary discriminating variables for slowness in men and women, respectively. Men with GRBMI of 1.05 kg/kg/m
conclusionGR with and without adjustments for body size and composition consistently discriminated older adults with slowness. CART models did not select DXA-based lean mass as a primary discriminator of slowness. These results were presented to an SDOC Consensus Panel, who used them and other information to develop the SDOC Position Statements. J Am Geriatr Soc 68:1419-1428, 2020.
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