Evidence map›Paper›PMID 32633726›Full record

ArticleAging2020

PHLPP2 is regulated by competing endogenous RNA network in pathogenesis of colon cancer.

Hong-Kun Wu, Chang Liu, Xin-Xing Li, Wei Ji, Chen-De Xin, Zhi-Qian Hu, Lin Zhou

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hong-Kun WuDepartment of Laboratory Medicine, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Chang LiuDepartment of Laboratory Medicine, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Xin-Xing LiDepartment of General Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Wei JiDepartment of Laboratory Medicine, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Chen-De XinDepartment of Laboratory Medicine, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Zhi-Qian HuDepartment of General Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Lin ZhouDepartment of Laboratory Medicine, Changzheng Hospital, Naval Medical University, Shanghai 200003, P.R. China.
Shanghai Changzheng Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, homologous pleckstrin-homology (PH)-domain leucine-rich-repeat protein phosphatases (PHLPP2) has been reported as a tumor suppressor in colon cancer. This study aimed to unravel the possible involvement of long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) regulating PHLPP2 in colon cancer. Expressions of candidate lncRNAs and miRNAs were verified by the RT-qPCR and Western blot analyses in colon cancer. The roles of candidate genes in colon cancer were investigated in HT-29 cells

Indexed as

Colonic NeoplasmsAdultAgedAged, 80 and overAnimalsCell ProliferationFemaleHeterograftsHT29 CellsHumansMaleMiceMice, NudeMicroRNAsMiddle AgedNeoplasm MetastasisMicroRNAsPHLPP2 protein, humanPhosphoprotein PhosphatasesRNA, Long NoncodingceRNAEMTlncRNAmiRNAPHLPP2

Identifiers

PMID32633726
PMCPMC7377866
OpenAlexW3040759642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.