Evidence map›Paper›PMID 32633519›Full record

ReviewJournal of proteome research2020

Metabolomics of Milk Reflects a Negative Energy Balance in Cows.

Wei Xu, Ariette van Knegsel, Edoardo Saccenti, Renny van Hoeij, Bas Kemp, Jacques Vervoort

Abstract readReview
In one paragraph

Review in Journal of proteome research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. Review
  3. Recent Trends in Metabolomics by NMR Spectroscopy.Angewandte Chemie (International ed. in English) · 2026
    Review
  4. Targeted metabolomics of organic and amino acids in giraffe milk during mid- to late-lactation.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  5. Animals : an open access journal from MDPI · 2026
    Article
  6. NMR Profiling of Milk from Treated Dried off Cows.Foods (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei XuAdaptation Physiology Group, Wageningen University & Research, Wageningen 6708 PB, the Netherlands.
Ariette van KnegselAdaptation Physiology Group, Wageningen University & Research, Wageningen 6708 PB, the Netherlands.
Edoardo SaccentiSystems and Synthetic Biology, Wageningen University & Research, Wageningen 6708 PB, the Netherlands.ORCID 0000-0001-8284-4829
Renny van HoeijAdaptation Physiology Group, Wageningen University & Research, Wageningen 6708 PB, the Netherlands.
Bas KempAdaptation Physiology Group, Wageningen University & Research, Wageningen 6708 PB, the Netherlands.
Jacques VervoortLaboratory of Biochemistry, Wageningen University & Research, Wageningen 6708 PB, the Netherlands.ORCID 0000-0002-0091-5687

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dairy cows can experience a negative energy balance (NEB) in early lactation when feed intake is too low to meet the energy requirements for body maintenance and milk production. Metabolic changes occur in mammary gland cells of animals experiencing a negative energy balance. We studied these metabolic changes in milk samples from dairy cows in relation to energy balance status using liquid chromatography-mass spectrometry (QQQ-LC-MS) and nuclear magnetic resonance (

Indexed as

LactationMilkAnimalsCattleDietEnergy MetabolismFemaleMetabolomicsTriglyceridesTriglyceridesenergy balanceintegrated analysisLC−MSmetabolic statusmetabolomicsmilkNMR

Identifiers

PMID32633519
PMCPMC7426013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.