Evidence map›Paper›PMID 32633507›Full record

ReviewJournal of agricultural and food chemistry2020

Recent Advances in Nanoencapsulation of Phytochemicals to Combat Obesity and Its Comorbidities.

Zeynep Goktas, Yujiao Zu, Mehrnaz Abbasi, Shannon Galyean, Dayong Wu, Zhaoyang Fan, Shu Wang

Open access · greenAbstract readReview
In one paragraph

Review in Journal of agricultural and food chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 79 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. RSC advances · 2026
    Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Recent advances in anti-infective drug discovery · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Zeynep GoktasFaculty of Health Sciences, Department of Nutrition and Dietetics, Hacettepe University, 06100 Ankara, Turkey.ORCID http://orcid.org/0000-0001-7241-8017
Yujiao ZuDepartment of Nutritional Sciences, Texas Tech University, Lubbock, Texas 79409, United States.
Mehrnaz AbbasiDepartment of Nutritional Sciences, Texas Tech University, Lubbock, Texas 79409, United States.
Shannon GalyeanDepartment of Nutritional Sciences, Texas Tech University, Lubbock, Texas 79409, United States.
Dayong WuNutrition Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, United States.
Zhaoyang FanDepartment of Electrical & Computer Engineering and Nano Tech Center, Texas Tech University, Lubbock, Texas 79409, United States.ORCID http://orcid.org/0000-0002-6185-2325
Shu WangDepartment of Nutritional Sciences, Texas Tech University, Lubbock, Texas 79409, United States.ORCID http://orcid.org/0000-0001-8078-9942
Texas Tech University · USHacettepe University · TRTufts University · US

Funding

Browning White Adipose Tissue for Diabetes TreatmentR15AT010395 · NCCIH · TEXAS TECH UNIVERSITY · PI DHURANDHAR, NIKHIL V · 2019 to 2019
$436k
Anti-obesity effects of adipose-targeting resveratrol nanocarriersR15AT008733 · NCCIH · TEXAS TECH UNIVERSITY · PI WANG, SHU · 2015 to 2015
$395k
NCCIH NIH HHS R15 AT008733NCCIH NIH HHS R15 AT010395
6 · The paper itself

Abstract

An increasing epidemic of obesity has become a serious public health concern primarily because it contributes to pathogenesis of many chronic diseases including type 2 diabetes, cardiovascular disease, hepatobiliary disease, obstructive sleep apnea, kidney disease, some types of cancer, among others. Consumption of a variety of phytochemicals has emerged as a promising potential for combating obesity and its comorbidities. However, the generally low aqueous solubility, stability, bioavailability, and target specificity of phytochemicals, along with their side-effects and toxicity seen when used at high doses, have restricted their clinical applications. As a solution, phytochemicals can be encapsulated into nanoparticles to increase their stability and solubility, enhance their bioavailability, protect them from premature degradation in the body, prolong their circulation time, and thus enhance their antiobesity activity. In this perspective, we summarize the problems and limitations of the prominent phytochemicals (epigallocatechin gallate,

Indexed as

AnimalsDrug CompoundingDrug Delivery SystemsHumansNanoparticlesPhytochemicalsPhytochemicalscurcuminepigallocatechin gallatenanoparticlesobesityquercetintrans-resveratrol

Identifiers

PMID32633507
PMCPMC8507418
OpenAlexW3042114731

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.