ArticleESC heart failure2020
Prevalence and prognostic impact of subclinical pulmonary congestion at discharge in patients with acute heart failure.
Article in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Lung Ultrasound in Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Replacement: a Prospective Study
Acetazolamide or Metolazone in Acute Heart Failure
Who cites it
48 citing papers in PubMed, 73 citations in OpenAlex.
- Impact of B-lines-guided intensive heart failure management on outcome of discharged heart failure patients with residual B-lines.ESC heart failure · 2022Trial
- Guiding Acute Heart Failure Treatment by Point-of-Care Ultrasound: Validation of a Score Combining Lung Ultrasound and Venous Excess Ultrasound.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026Article
- Article
- Point-of-Care Ultrasonography in Advanced Nephrology Nursing Practice: Seeing Beyond the Numbers.Diagnostics (Basel, Switzerland) · 2025Review
- Lung ultrasound in cardiac rehabilitation: expert consensus on protocols, clinical use, and integration into patient management from the working group on cardiac rehabilitation and cardiovascular prevention of the Italian society of cardiology.Heart failure reviews · 2025Review
- Assessing Venous Congestion in Acute and Chronic Heart Failure: A Review of Splanchnic, Cardiac and Pulmonary Ultrasound: Part 1: Conventional B-Mode, Colordoppler, and Vexus Protocol.Journal of clinical medicine · 2025Review
- Streamlining heart failure patient care with machine learning of thoracic cavity sound data.World journal of cardiology · 2025Review
- Prognostic Utility of HEFESTOS Score and Complementary Lung Ultrasound for Heart Failure Decompensation in Primary Care Outpatients: A Prospective Cohort Study.Journal of cardiovascular development and disease · 2025Article
- Venous Excess Ultrasound (VExUS) score and short-term outcomes in ambulatory patients with heart failure with reduced ejection fraction: an exploratory study.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
- Interest of Lung Ultrasound in the Management of Acute Heart Failure in Post-Emergency Service.Life (Basel, Switzerland) · 2025Article
- Door-to-Diuretic Time and Outcomes in Acute Heart Failure: A Scoping Review.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025Article
- Assessment of Decongestion Status Before Discharge in Acute Decompensated Heart Failure: A Review of Clinical, Biochemical, and Imaging Tools and Their Impact on Management Decisions.Medicina (Kaunas, Lithuania) · 2025Review
- Ultrasound imaging of congestion in heart failure: a narrative review.Cardiovascular diagnosis and therapy · 2025Review
- Predictive Value of Lung Ultrasound Combined With ACEF Score for the Prognosis of Acute Myocardial Infarction.Clinical cardiology · 2025Article
- Assessing congestion using estimated plasma volume status: Ready for prime time?ESC heart failure · 2025Article
- Addressing 'Residual Congestion' to Improve Prognosis After Acute Heart Failure Decompensation.Cardiac failure review · 2025Review
- Biomarkers for Congestion in Heart Failure: State-of-the-art and Future Directions.Cardiac failure review · 2025Review
- The Role of Lung Ultrasound Scan in Different Heart Failure Scenarios: Current Applications and Lacks of Evidences.Diagnostics (Basel, Switzerland) · 2024Review
- Lung Ultrasound in the Acute Phase of ST-Segment-Elevation Acute Myocardial Infarction: 1-Year Prognosis and Improvement in Risk Prediction.Journal of the American Heart Association · 2024Article
- Assessment of Pulmonary Congestion According to Ultrasound and Remote Dielectric Sensing (ReDS) in Patients Hospitalized With Heart Failure.Arquivos brasileiros de cardiologia · 2024Article
Corrections and comments
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Authors and funding
16 authors at 3 institutions in 1 country.
Funding
Abstract
aimsResidual pulmonary congestion at hospital discharge can worsen the outcomes in patients with heart failure (HF) and can be detected by lung ultrasound (LUS). The aim of this study was to analyse the prevalence of subclinical pulmonary congestion at discharge and its impact on prognosis in patients admitted for acute HF. METHODS AND
resultsThis is a post-hoc analysis of the LUS-HF trial. LUS was performed by the investigators in eight chest zones with a pocket device. Physical exam was subsequently performed by the treating physicians. Primary outcome was a combined endpoint of rehospitalization, unexpected visit for HF worsening or death at 6- month follow-up. Subclinical pulmonary congestion at discharge was defined as the presence of ≥5 B-lines in LUS in absence of rales in the auscultation employing the area under the ROC curve. At discharge, 100 patients (81%) did not show clinical signs of pulmonary congestion. Of these, 41 had ≥5 B-lines. Independent factors related with the presence of subclinical pulmonary congestion were anaemia, higher New York Heart Association (NYHA) class, and N terminal pro brain natriuretic peptide (NT-proBNP). After adjusting by propensity score analysis including age, renal insufficiency, atrial fibrillation, NYHA class, NT-proBNP levels, clinical congestion, and the trial intervention, the presence of subclinical pulmonary congestion at discharge was a risk factor for the occurrence of the primary outcome (hazard ratio 2.63; 95% confidence interval: 1.08-6.41; P = 0.033).
conclusionsUp to 40% of patients considered 'dry' according to pulmonary auscultation presents subclinical congestion at hospital discharge that can be detected by LUS and implies a worse prognosis at 6- month follow-up. Comorbidities, high values of natriuretic peptides, and higher NYHA class are the factors related with its presence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.