SynthesisInternational wound journal2020
The application of platelet-rich plasma for skin graft enrichment: A meta-analysis.
Synthesis in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05511493 (Efficacy of Platelet-rich Plasma With Fractional Erbium-YAG Laser Versus With Microneedling in Localized Stable Vitiligo), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Platelet-rich Plasma With Fractional Erbium-YAG Laser Versus With Microneedling in Localized Stable Vitiligo
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Current art of combination therapy with autologous platelet-rich plasma for stable vitiligo: A meta-analysis.International wound journal · 2021Pooled it
- The application of platelet-rich plasma for skin graft enrichment: A meta-analysis.International wound journal · 2020Pooled it
- Effectiveness of Platelet-Rich Plasma Combined with Split-Thickness Skin Grafts for Skin Defects: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Standardized Preparation and Multi-Site Application of Leukocyte-Poor Platelet-Rich Plasma in Arthroscopic Anterior Cruciate Ligament Reconstruction: A Technical Note with Early Functional Outcomes.Journal of orthopaedic case reports · 2026Article
- Injectable Fillers for Atrophic Acne Scars: A Systematic Review of Mechanisms, Evidence, and Clinical Algorithms.Clinical, cosmetic and investigational dermatology · 2026Review
- Bioengineered Skin from a Platelet-Derived Hydrogel Repairs Full Thickness Wounds in a Pre-Clinical Mouse Model.International journal of molecular sciences · 2025Article
- Article
- Comparison effects of platelet-rich plasma on healing of infected and non-infected excision wounds by the modulation of the expression of inflammatory mediators: experimental research.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Free Skin Grafting to Reconstruct Donor Sites after Radial Forearm Flap Harvesting: A Prospective Study with Platelet-Rich Fibrin (PRF).Journal of clinical medicine · 2022Article
- Techniques to Enhance Survival of Auricular Composite Graft in Reconstruction of Skin Defects of the Nasal Ala and Nasal Sidewall: A Case Report.World journal of plastic surgery · 2022Article
- Moving toward targeting the right phenotype with the right platelet-rich plasma (PRP) formulation for knee osteoarthritis.Therapeutic advances in musculoskeletal disease · 2021Review
- Platelet-rich plasma (PRP) for skin graft enrichment: The need for a universal PRP classification system.International wound journal · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Existing evidence demonstrated that the role of platelet-rich plasma (PRP) in skin graft enrichment is uncertain. The aim of this study was to evaluate the efficacy and safety of PRP for skin graft. PubMed, EMBASE, Web of Science, and Cochrane Library databases were searched for randomised controlled trials that compared outcomes of skin graft treated with PRP versus those treated with blank controls. The outcomes mainly included the rate of skin graft take, number of skin graft loss and haematoma formation, and complications. There were 11 studies involving a total of 910 cases of skin grafts. Compared with the control group, PRP group had a significantly higher rate of skin graft take (mean difference = 5.47%; 95% confidence interval [CI], 2.80%-8.14%; P < .0001), fewer number of skin graft loss (risk ratio [RR] = 0.26; 95% CI, 0.13-0.55; P = .0004) and fewer cases of haematoma formation (RR = 0.24; 95% CI, 0.11-0.54; P = .0006). There was no significant difference in the incidence of complications between two groups. This meta-analysis summarises current evidence and indicates that PRP is a safe and effective adjuvant for skin graft enrichment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.