Evidence map›Paper›PMID 32633327›Full record

ReviewPathogens and disease2020

SARS, MERS and COVID-19: clinical manifestations and organ-system complications: a mini review.

Jad Gerges Harb, Hussein A Noureldine, Georges Chedid, Mariam Nour Eldine, Dany Abou Abdallah, Nancy Falco Chedid, Wared Nour-Eldine

Open access · bronzeAbstract readReview
In one paragraph

Review in Pathogens and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
1.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 75 citations in OpenAlex.

  1. Observational
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  16. Editorial: High-impact respiratory RNA virus diseases.Frontiers in veterinary science · 2023
    Article
  17. Article
  18. What might COVID-19 patients experience after recovery? A comprehensive review.The International journal of pharmacy practice · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jad Gerges HarbGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Hussein A NoureldineGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Georges ChedidGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Mariam Nour EldineGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Dany Abou AbdallahLebanese University, Faculty of Medical Sciences, Rafik Hariri University Campus, Hadath, Lebanon.
Nancy Falco ChedidGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Wared Nour-EldineGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Lebanese American University · LBLebanese University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Middle East Respiratory Syndrome (MERS), Severe Acute Respiratory Syndrome (SARS) and Coronavirus Disease 2019 (COVID-19) are caused by three distinct coronaviruses belonging to the same genus. COVID-19 and its two predecessors share many important features in their clinical presentations, and in their propensity for progression to severe disease which is marked by high rates of morbidity and mortality. However, comparison of the three viral illnesses also reveals a number of specific differences in clinical manifestations and complications, which suggest variability in the disease process. This narrative review delineates the pulmonary, cardiac, renal, gastrointestinal, hepatic, neurological and hematologic complications associated with these three respiratory coronaviruses. It further describes the mechanisms of immune hyperactivation-particularly cytokine release syndrome-implicated in the multi-organ system injury seen in severe cases of MERS, SARS and COVID-19.

Indexed as

Acute Kidney InjuryCoronavirus InfectionsCOVID-19Cytokine Release SyndromeGastrointestinal DiseasesHeart FailureHumansLiver Failure, AcuteNervous System DiseasesPandemicsPneumonia, ViralRespiratory InsufficiencySevere Acute Respiratory Syndromeacute hepatic injuryacute kidney injuryacute neurologic syndromeacute respiratory distress syndromecentral neurogenic respiratory failurecoronavirus disease 2019cytokine release syndromeheart failureMiddle East respiratory syndrome coronaviruspneumoniasevere acute respiratory syndrome coronavirus 1severe acute respiratory syndrome coronavirus 2

Identifiers

PMID32633327
PMCPMC7454523
OpenAlexW3038544108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.