Evidence map›Paper›PMID 32632890›Full record

ArticleSpine deformity2020

Cost-effectiveness of adult lumbar scoliosis surgery: an as-treated analysis from the adult symptomatic scoliosis surgery trial with 5-year follow-up.

Steven D Glassman, Leah Y Carreon, Christopher I Shaffrey, Michael P Kelly, Charles H Crawford, Elizabeth L Yanik, Jon D Lurie, R Shay Bess, Christine R Baldus, Keith H Bridwell

Open access · greenAbstract readComparative Study
In one paragraph

Article in Spine deformity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Extent of fatty infiltration in lumbar paraspinal muscles in adults with degenerative scoliosis: segmental differences in muscle involvement.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Comparison of quality of life between operated and non-operated adults with painful degenerative scoliosis: a 2-year prospective multicentered observational study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Observational
  6. Article
  7. Iatrogenic posterior translation of the construct at the uppermost instrumented vertebrae is associated with proximal junctional kyphosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
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  10. Readmission rate after adult scoliosis surgery on primary cases over 45 years-old with long term follow-up.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
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  14. Osteobiologics and Value-Based Care: Challenges and Opportunities.International journal of spine surgery · 2023
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Steven D GlassmanNorton Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY, 40202, USA.
Leah Y CarreonNorton Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY, 40202, USA. leah.carreon@nortonhealthcare.org.ORCID http://orcid.org/0000-0002-7685-9036
Christopher I ShaffreyDuke University Duke Spine Center-Clinic 1B/1C, 40 Duke Medicine Circle, Durham, NC, 27710-400, USA.
Michael P KellyDepartment of Orthopaedic Surgery, Washington University School of Medicine, 660 S. Euclid Ave, Campus Box 8233, St. Louis, MO, 63110, USA.
Charles H CrawfordNorton Leatherman Spine Center, 210 East Gray Street, Suite 900, Louisville, KY, 40202, USA.
Elizabeth L YanikDepartment of Orthopaedic Surgery, Washington University School of Medicine, 660 S. Euclid Ave, Campus Box 8233, St. Louis, MO, 63110, USA.
Jon D LurieDepartments of Medicine and Orthopaedics, Dartmouth-Hitchcock Medical Center, One Medical Center Dr., Lebanon, NH, 03756, USA.
R Shay BessDepartment of Orthopaedic Surgery, Rocky Mountain Hospital for Children, 1721 E. 19th Ave., Suite 244, Denver, CO, 80218, USA.
Christine R BaldusDuke University Duke Spine Center-Clinic 1B/1C, 40 Duke Medicine Circle, Durham, NC, 27710-400, USA.
Keith H BridwellDuke University Duke Spine Center-Clinic 1B/1C, 40 Duke Medicine Circle, Durham, NC, 27710-400, USA.
Duke University · USUniversity of Louisville · USWashington University in St. Louis · USDartmouth–Hitchcock Medical Center · USNorton Healthcare · USRocky Mountain Hospital for Children · US

Funding

A Mulit-Centered Prospective Study of Quality of Life in Adult ScoliosisR01AR055176 · NIAMS · WASHINGTON UNIVERSITY · PI BRIDWELL, KEITH HAPP · 2009 to 2014
$2.4M
NIAMS NIH HHS R01 AR055176
6 · The paper itself

Abstract

STUDY

designLongitudinal comparative cohort.

objectiveThe purpose of this study is to report on the cost-effectiveness of surgical versus non-surgical treatment for Adult Symptomatic Lumbar Scoliosis (ASLS) using the as-treated data and provide a comparison to previously reported intent-to-treat (ITT) analysis. Adult spinal deformity is a relatively prevalent condition for which surgical treatment has become increasingly common but concerns surrounding complications, revision rates and cost-effectiveness remain unresolved. Of these issues, cost-effectiveness is perhaps the most difficult to quantify as the requisite data is difficult to obtain. The purpose of this study is to report on the cost-effectiveness of surgical versus non-surgical treatment for ASLS using the as-treated data and provide a comparison to previously reported ITT analysis.

methodsPatients with at least 5-year follow-up data within the same treatment arm were included. Data collected every 3 months included use of nonoperative modalities, medications and employment status. Costs for surgeries and non-operative modalities were determined using Medicare Allowable rates. Medication costs were determined using the RedBook and indirect costs were calculated based on the reported employment status and income. Quality-Adjusted Life Years (QALY) was determined using the SF-6D.

resultsOf 226 patients, 195 patients (73 Non-op, 122 Op) met inclusion criteria. At 5 years, 29 (24%) patients in the Op group had a revision surgery of whom two had two revisions and one had three revisions. The cumulative cost for the Op group was $111,451 with a cumulative QALY gain of 2.3. The cumulative cost for the Non-Op group was $29,124 with a cumulative QALY gain of 0.4. This results in an ICER of $44,033 in favor of Op treatment.

conclusionThis as-treated cost-effectiveness analysis demonstrates that surgical treatment for adult lumbar scoliosis becomes favorable at year-three, 1 year earlier than suggested by a previous intent-to-treat analysis. LEVEL OF EVIDENCE: II.

Indexed as

AdultAgedAged, 80 and overCohort StudiesConservative TreatmentCost-Benefit AnalysisFemaleFollow-Up StudiesHumansLumbar VertebraeMaleMiddle AgedScoliosisSpinal FusionTime FactorsAs-treated analysisCost-effectivenessLumbar scoliosisOperative vs non-operative

Identifiers

PMID32632890
PMCPMC7708503
OpenAlexW3039006520

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.