Evidence map›Paper›PMID 32632880›Full record

ReviewAnnals of surgical oncology2020

The Landmark Series: Neuroendocrine Tumor Liver Metastases.

Alexandra Gangi, James R Howe

Open access · greenAbstract readReview
In one paragraph

Review in Annals of surgical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 39 citations in OpenAlex.

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  14. Parametric net influx rate imaging ofAnnals of nuclear medicine · 2024
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  16. Comparison ofCurrent oncology (Toronto, Ont.) · 2024
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Alexandra GangiDivision of Surgical Oncology, Department of Surgery, Cedars Sinai Medical Center, 8700 Beverly Blvd, AC 1049, Los Angeles, CA, 90048, USA.
James R HoweSurgical Oncology and Endocrine Surgery, University of Iowa Carver College of Medicine, University of Iowa Hospitals and Clinics, 4644 JCP, 200 Hawkins Drive, Iowa City, IA, 52242, USA. james-howe@uiowa.edu.
Cedars-Sinai Medical Center · USUniversity of Iowa Hospitals and Clinics · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
Project 4: New Approaches to Improving the Effectiveness of Radionuclide Targeted Treatments in Neuroendocrine TumorsP50CA174521 · NCI · UNIVERSITY OF IOWA · PI ODORISIO, THOMAS · 2015 to 2021
$13.2M
NCI NIH HHS P50 CA174521SPORE in Neuroendocrine Tumors P50 CA174521-01
6 · The paper itself

Abstract

backgroundNeuroendocrine tumors are becoming increasingly prevalent, with many patients presenting with or developing metastatic disease to the liver.

methodsIn this landmark series paper, we highlight the critical studies that have defined the surgical management of neuroendocrine tumor liver metastases, as well as several randomized control trials which have investigated strategies for systemic control of metastatic disease.

resultsLiver-directed surgical approaches and locally ablative procedures are recommended for patients with limited, resectable, and in some cases, nonresectable tumor burden. Angiographic liver-directed techniques, such as transarterial embolization, chemoembolization, and radioembolization, offer another approach for management in patients with liver-predominant disease. Peptide receptor radionuclide therapy is a promising therapy for patients with hepatic and/or extrahepatic metastases. Various systemic medical therapies are also available as adjunct or definitive therapy for patients with metastatic disease.

conclusionsThis article reviews current data regarding management of neuroendocrine liver metastases and highlights areas for future study.

Indexed as

Liver NeoplasmsNeuroendocrine TumorsChemoembolization, TherapeuticHumansRadioisotopesRandomized Controlled Trials as TopicTumor BurdenRadioisotopesLiver debulkingLiver metastasesNeuroendocrinePRRT

Identifiers

PMID32632880
PMCPMC7415723
OpenAlexW3039097298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.