Evidence map›Paper›PMID 32632746›Full record

ReviewSports medicine (Auckland, N.Z.)2020

Overlapping Mechanisms of Exertional Heat Stroke and Malignant Hyperthermia: Evidence vs. Conjecture.

Orlando Laitano, Kevin O Murray, Lisa R Leon

Abstract readReview
PubMed Publisher
In one paragraph

Review in Sports medicine (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Phosphorylation of RYR1 at SerScience signaling · 2025
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  8. Review
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  14. Article
  15. Review
  16. Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Article
  18. Article
  19. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Orlando LaitanoDepartment of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, 1864 Stadium Road, Room 100, Gainesville, FL, USA. orlando.laitano@ufl.edu.ORCID http://orcid.org/0000-0003-2768-1427
Kevin O MurrayDepartment of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, 1864 Stadium Road, Room 100, Gainesville, FL, USA.
Lisa R LeonThermal and Mountain Medicine Division, US Army Research Institute for Environmental Medicine, Natick, MA, USA.
University of Florida · USU.S. Army Research Institute of Environmental Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exertional heat stroke (EHS) and malignant hyperthermia (MH) are life-threatening conditions, triggered by different environmental stimuli that share several clinical symptoms and pathophysiological features. EHS manifests during physical activity normally, but not always, in hot and humid environments. MH manifests during exposure to haloalkane anesthetics or succinylcholine, which leads to a rapid, unregulated release of calcium (Ca

Indexed as

Heat StrokeMalignant HyperthermiaMuscle ContractionAnestheticsCalciumCalcium Channel BlockersDantroleneHumansRyanodine Receptor Calcium Release ChannelAnestheticsCalciumCalcium Channel BlockersDantroleneRyanodine Receptor Calcium Release Channel

Identifiers

PMID32632746
OpenAlexW3039788863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.