Evidence map›Paper›PMID 32632743›Full record

ArticleEuropean biophysics journal : EBJ2020

Model lipid systems and their use to evaluate the phase state of biomembranes, their mechanical properties and the effect of non-conventional antibiotics: the case of daptomycin.

Daniel Balleza, Andrea Mescola, Andrea Alessandrini

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in European biophysics journal : EBJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Daniel BallezaInstituto Tecnológico de Educación Superior, Zapopan, 45138, Jalisco, Mexico. dballezam@itea.edu.mx.ORCID http://orcid.org/0000-0002-6848-9135
Andrea MescolaCNR-Nanoscience Institute-S3, Via Campi 213/A, 41125, Modena, Italy.
Andrea AlessandriniCNR-Nanoscience Institute-S3, Via Campi 213/A, 41125, Modena, Italy.
Instituto Tecnológico Superior de Xalapa · MXIstituto Nanoscienze · ITUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lipid bilayer is the basis of the structure and function of the cell membrane. The study of the molecular phenomena that affect biological membranes has a great impact on the understanding of cellular physiology. To understand these phenomena, it has become increasingly necessary to develop simple synthetic models that allow the most basic details of such processes to be reproduced. In this short communication, we took advantage of the properties of two well-established lipid model systems, GUVs and SLBs, with compositions mimicking the cell membrane present in mammals and bacteria, to study the thermotropic phase behavior of lipids as well as the effect of daptomycin, a cyclic lipopeptide used as an antibiotic. The study of mechanical and thermodynamical properties of these model systems could contribute to establish a theoretical framework to develop more efficient strategies for biological control.

Indexed as

Models, MolecularAnti-Bacterial AgentsBiomechanical PhenomenaCell MembraneDaptomycinMechanical PhenomenaMolecular ConformationUnilamellar LiposomesAnti-Bacterial AgentsDaptomycinUnilamellar LiposomesDaptomycinLipid bilayersLiposomes

Identifiers

PMID32632743
OpenAlexW3039285929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.