ArticleMolecular psychiatry2021
MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis.
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Article in Molecular psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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49citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Non-coding RNAs involved in the molecular pathology of Alzheimer's disease: a systematic review.Frontiers in neuroscience · 2024Pooled it
- Expression levels of miR-132, miR-134, and miR-195 in treatment-naïve children and adolescents with obsessive-compulsive disorder: a case-control study.BMC psychiatry · 2026Article
- MicroRNAs and Long Non-Coding RNAs Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on RNA-Binding Proteins.Molecular neurobiology · 2026Review
- Role of microRNAs in major brain diseases, focusing on neuroinflammation and neuronal apoptosis.Iranian journal of basic medical sciences · 2026Review
- Epigenetic Changes in Alzheimer's Disease and Interventions for Therapy.Neuropsychiatric disease and treatment · 2026Review
- Toward nanomedicine-enabled RNA therapeutics for Alzheimer's disease.Molecular neurodegeneration advances · 2026Review
- MicroRNAs in the biology and hallmarks of neurodegenerative diseases.Trends in molecular medicine · 2025Review
- A novel miR-4536-3p inhibition ameliorates Alzheimer's disease by reducing Aβ accumulation and tau phosphorylation.Alzheimer's research & therapy · 2025Article
- Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Article
- Protein swarm-based cause-effect analysis: effects of microRNAs on cooperation networks linking COVID-19 infections, atherosclerosis, and Alzheimer's disease.Frontiers in cardiovascular medicine · 2025Article
- FN1, a reliable prognostic biomarker for thyroid cancer, is associated with tumor immunity and an unfavorable prognosis.Oncology letters · 2024Article
- Air Pollution as an Environmental Risk Factor for Alzheimer's Disease and Related Dementias.Medical research archives · 2024Article
- MicroRNAs: pioneering regulators in Alzheimer's disease pathogenesis, diagnosis, and therapy.Translational psychiatry · 2024Review
- BetaZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
- Exploring the Regulatory Landscape of Dementia: Insights from Non-Coding RNAs.International journal of molecular sciences · 2024Review
- Role of Epigenetic Modulation in Neurodegenerative Diseases: Implications of Phytochemical Interventions.Antioxidants (Basel, Switzerland) · 2024Review
- Article
- microRNA and the Post-Transcriptional Response to Oxidative Stress during Neuronal Differentiation: Implications for Neurodevelopmental and Psychiatric Disorders.Life (Basel, Switzerland) · 2024Article
- Alzheimer's Disease-Related Epigenetic Changes: Novel Therapeutic Targets.Molecular neurobiology · 2024Review
- Noncoding RNAs in Alzheimer's Disease: Overview of Functional and Therapeutic Significance.Current topics in medicinal chemistry · 2024Review
Corrections and comments
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Authors and funding
16 authors at 3 institutions in 1 country.
Jiqing Cao *James J Peters VA Medical Center, Research & Development, Bronx, NY, 10468, USA.
Min Huang *James J Peters VA Medical Center, Research & Development, Bronx, NY, 10468, USA.
Lei GuoDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Li ZhuJames J Peters VA Medical Center, Research & Development, Bronx, NY, 10468, USA.
Jianwei HouJames J Peters VA Medical Center, Research & Development, Bronx, NY, 10468, USA.
Larry ZhangJames J Peters VA Medical Center, Research & Development, Bronx, NY, 10468, USA.
Adriana PeroJames J Peters VA Medical Center, Research & Development, Bronx, NY, 10468, USA.
Sabrina NgJames J Peters VA Medical Center, Research & Development, Bronx, NY, 10468, USA.
Farida El GaamouchDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Gregory ElderJames J Peters VA Medical Center, Research & Development, Bronx, NY, 10468, USA.
Mary SanoJames J Peters VA Medical Center, Research & Development, Bronx, NY, 10468, USA.
Alison GoateDepartment of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.ORCID http://orcid.org/0000-0002-0576-2472
Julia TcwDepartment of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.ORCID http://orcid.org/0000-0002-3054-9374
Vahram HaroutunianDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Bin ZhangDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Dongming CaiJames J Peters VA Medical Center, Research & Development, Bronx, NY, 10468, USA. dongming.cai@mssm.edu.ORCID http://orcid.org/0000-0002-0601-6826
James J. Peters VA Medical Center · USIcahn School of Medicine at Mount Sinai · USCornell University · US
Funding
Research Education ComponentP30AG066514 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI NIKOLAOS K ROBAKIS · 2020 to 2026
$31.0MIntegrative Network Biology Approaches to Identify, Characterize and Validate Molecular Subtypes in Alzheimer's DiseaseU01AG046170 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WANG, MINGHUI, ZHANG, BIN · 2013 to 2022
$26.0MGenomic approach to identification of microglial networks involved in Alzheimer’s disease riskU01AG058635 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GOATE, ALISON M · 2018 to 2022
$4.8MIdentification and characterization of AD risk networks using multi-dimensional "omics" dataU01AG052411 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CRUCHAGA, CARLOS, GOATE, ALISON M · 2016 to 2020
$4.5MMolecular Characterization and Validation of Gender Differences in Alzheimers Disease PathogenesisRF1AG054014 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CAI, DONGMING, ZHANG, BIN · 2016 to 2016
$4.2MTranscriptional Control of Neuroinflammation in Alzheimer's DiseaseR01AG072562 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CAI, DONGMING, ZHOU, MING-MING · 2021 to 2025
$4.2MSYSTEMATIC DRUG REPURPOSING TARGETING IMMUNE ACTIVATION NETWORKS IN ALZHEIMER'S DISEASE (AD)RF1AG059319 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI EHRLICH, MICHELLE E, GANDY, SAMUEL E. · 2018 to 2018
$4.2MTowards a comprehensive signaling pathway map of parahippocampal vulnerability in Alzheimers DiseaseRF1AG057440 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HAROUTUNIAN, VAHRAM, NOGGLE, SCOTT ALLEN · 2017 to 2017
$3.5MCharacterization of ApoE4 Induced Phospholipid Dysregulation in AD PathogenesisR01AG048923 · NIA · UNIVERSITY OF MINNESOTA · PI CAI, DONGMING · 2015 to 2025
$3.1MCharacterization of ApoE4 Induced Phospholipid Dysregulation in AD PathogenesisRF1AG048923 · NIA · UNIVERSITY OF MINNESOTA · PI CAI, DONGMING · 2021 to 2021
$2.1MCharacterization of protective roles of ApoE2 against aging and Alzheimer's diseaseR56AG058655 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CAI, DONGMING, LADU, MARY JO · 2019 to 2019
$841kDeciphering isogenic APOE isoform dependent neurodegenerative response in human gliaK01AG062683 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI TCW, JULIA · 2019 to 2023
$621kBLRD VA I01 BX003380CSRD VA I01 CX000619NIA NIH HHS K01 AG062683NIA NIH HHS P30 AG066514NIA NIH HHS R01 AG048923NIA NIH HHS R01 AG072562NIA NIH HHS R56 AG058655NIA NIH HHS RF1 AG048923NIA NIH HHS RF1 AG054014NIA NIH HHS RF1 AG057440NIA NIH HHS RF1 AG059319NIA NIH HHS U01 AG046170NIA NIH HHS U01 AG052411NIA NIH HHS U01 AG058635RRD VA I01 RX002290RRD VA I01 RX002660
Abstract
Our recent findings link the apolipoprotein E4 (ApoE4)-specific changes in brain phosphoinositol biphosphate (PIP
Indexed as
Alzheimer DiseaseCognitive DysfunctionMicroRNAsAmyloid beta-PeptidesAnimalsApolipoprotein E4CognitionHumansLysosomesMiceMice, TransgenicAmyloid beta-PeptidesApolipoprotein E4MicroRNAsMIRN195 microRNA, human
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.