SynthesisScientific reports2020
Plasmodium spp. mixed infection leading to severe malaria: a systematic review and meta-analysis.
Synthesis in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
56 citing papers in PubMed, 7 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Prevalence of malaria and its major parasite species in Bangladesh: a systematic review and meta-analysis.Malaria journal · 2026Pooled it
- Cyclodextrins as a Strategy for Enhancing Solubility of Therapeutic Agents for Neglected Tropical Diseases: A Systematic Review.Current medicinal chemistry · 2025Pooled it
- The impact of different antibiotic injection regimens on patients with severe infections: A meta-analysis.International wound journal · 2024Pooled it
- Prevalence of Signs of Severity Identified in the Thai Population with Malaria: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Comparison of Plasmodium ovale curtisi and Plasmodium ovale wallikeri infections by a meta-analysis approach.Scientific reports · 2021Pooled it
- Comorbidity of Geo-Helminthes among Malaria Outpatients of the Health Facilities in Ethiopia: Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Misidentification of Plasmodium ovale as Plasmodium vivax malaria by a microscopic method: a meta-analysis of confirmed P. ovale cases.Scientific reports · 2020Pooled it
- Detection ofASM case reports · 2026Article
- Prevalence of Plasmodium ovale and Plasmodium malariae Mixed Infections and Associated Mortality in Children with Severe Falciparum Malaria.The American journal of tropical medicine and hygiene · 2026Article
- Hidden hematological, biochemical and immune costs of asymptomatic malaria infections in semi-wild chimpanzees.PLoS pathogens · 2026Article
- Mechanisms of carbamate resistance in the malaria vector:Parasite epidemiology and control · 2026Review
- High Burden of Febrile Sub-microscopic Plasmodium Mixed Infections in Central India: A Cross-Sectional Study.Infectious diseases and therapy · 2026Article
- Evaluating the diagnostic performance of miLab™ for detection of malaria parasites using nPCR as reference standard.Malaria journal · 2026Article
- Article
- Mixed malaria infections: A critical review and Detect-Characterise-Act surveillance framework.Current research in parasitology & vector-borne diseases · 2026Review
- Prevalence and Type Distribution of Malaria Among Children in Ethiopia: A Systematic Review and Meta-Analysis.Journal of parasitology research · 2026Review
- What impact did the Brazilian Federal Government's intervention have on malaria cases in the Yanomami Indigenous lands?Malaria journal · 2025Article
- Review
- Hidden hematological, biochemical and immune costs of asymptomatic malaria infections in semi-wild chimpanzees.bioRxiv : the preprint server for biology · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mixed Plasmodium malaria infections can lead to severe malaria. This systematic review and meta-analysis aimed to explore the prevalence of severe mixed Plasmodium malaria infection and to compare it with the prevalence of severe P. falciparum malaria mono-infection across the included studies. Original English-language research articles from PubMed, Scopus, and ISI Web of Science were identified and screened. Articles reporting the number of mixed infections and the number of severe mixed infections were used to determine the main outcome of this study, while the number of P. falciparum infections and the number of severe P. falciparum infections were used to determine the secondary outcome of this study. For the main outcome, the pooled prevalence and 95% confidence interval (CI) of severe mixed infections was analysed using STATA software version 15.0 (Stata Corp, College Station, TX, USA). For the secondary outcome, the rate of severe mixed infections compared to severe P. falciparum infections was analysed using the meta-analysis approach, and summary odds ratios (ORs) and 95% CIs were calculated. Random-effects models were used to produce the summary ORs. The Mantel-Haenszel method and calculated I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.