ArticleNature communications2020
Requirements for the differentiation of innate T-bet
Erratum issuedOpen access · goldAbstract read
In one paragraph
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- Virus-specific memory CD4 T cells sustain long-term numerical and functional impairment following whole-body irradiation.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Whole-body irradiation causes long-term impairments in the maintenance and function of naïve CD4 T cells specific for self- and non-self-antigens.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Increased Constitutive Interferon-β Levels and Altered CD4 T Cell Homeostasis Induced by Expression of a Viral Glycoprotein.European journal of immunology · 2026Article
- Th1-poised naive CD4 T cell subpopulation reflects anti-tumor immunity and autoimmune disease.Nature communications · 2025Article
- Naturally arising memory-phenotype CD4Science advances · 2024Article
- Excess generation and activation of naturally arising memory-phenotype CD4Frontiers in immunology · 2024Article
- Homeostatic cytokines reciprocally modulate the emergence of prenatal effector PLZF+CD4+ T cells in humans.JCI insight · 2023Article
- Steady-state memory-phenotype conventional CD4Experimental & molecular medicine · 2023Article
- The endogenous repertoire harbors self-reactive CD4Nature immunology · 2023Article
- Memory-phenotype CD4JMA journal · 2022Review
- Age-dependent rise in IFN-γ competence undermines effective type 2 responses to nematode infection.Mucosal immunology · 2022Article
- Memory-phenotype CD4+ T cells: a naturally arising T lymphocyte population possessing innate immune function.International immunology · 2022Review
- Immune Dysregulation in Autism Spectrum Disorder: What Do We Know about It?International journal of molecular sciences · 2022Review
- Redefining the Foreign Antigen and Self-Driven Memory CD4Frontiers in immunology · 2022Article
- Homeostasis of Naive and Memory T Lymphocytes.Cold Spring Harbor perspectives in biology · 2021Review
- Global Gene Expression of T Cells Is Differentially Regulated by Peritoneal Dendritic Cell Subsets in an IL-2 Dependent Manner.Frontiers in immunology · 2021Article
- "An Intrinsic Program Determines Key Age-Associated Changes in Adaptive Immunity that Limit Response to Non-Pathogens."Frontiers in aging · 2021Article
- Expression Regulation and Function of T-Bet in NK Cells.Frontiers in immunology · 2021Review
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 5 institutions in 4 countries.
Takeshi KawabeImmunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, 20892, USA. kawabet@med.tohoku.ac.jp.ORCID http://orcid.org/0000-0001-7173-4472
Jaeu YiAcademy of Immunology and Microbiology, Institute for Basic Science, Pohang, 37666, Republic of Korea.
Akihisa KawajiriDepartment of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.
Kerry HilliganImmunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
Difeng FangMolecular and Cellular Immunoregulation Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, 20892, USA.ORCID http://orcid.org/0000-0003-2105-6743
Naoto IshiiDepartment of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.
Hidehiro YamaneCellular Immunology Section, Vaccine Research Center, NIAID, NIH, Bethesda, MD, 20892, USA.
Jinfang ZhuMolecular and Cellular Immunoregulation Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, 20892, USA.
Dragana JankovicImmunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
Kwang Soon KimAcademy of Immunology and Microbiology, Institute for Basic Science, Pohang, 37666, Republic of Korea.
Giorgio TrinchieriCancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, 20892, USA.ORCID http://orcid.org/0000-0001-5892-7464
Alan SherImmunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, 20892, USA. asher@niaid.nih.gov.ORCID http://orcid.org/0000-0001-7053-2895
National Institutes of Health · USNational Institute of Allergy and Infectious Diseases · USPohang University of Science and Technology · KRTohoku University · JPNational Cancer Institute · US
Funding
Transcriptional Regulation of Immune Cell Development, Activation and FunctionsZIAAI001169 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ZHU, JINFANG · 2012 to 2025
$21.8MInnate Determinants of Microbial ImmunityZIAAI001044 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SHER, ALAN · 2009 to 2022
$8.8MRegulation of human dendritic cell activationZIABC011152 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI TRINCHIERI, GIORGIO · 2009 to 2025
$8.6MAbstract
CD4
Indexed as
AnimalsCD40 AntigensCD40 LigandCD4-Positive T-LymphocytesCD8 AntigensCell CommunicationCell DifferentiationDendritic CellsHomeostasisImmunologic MemoryInterleukin-12Mice, Inbred C57BLMice, KnockoutPhenotypeSignal TransductionT-bet Transcription FactorCD40 AntigensCD40 LigandCD8alpha antigenCD8 AntigensInterleukin-12T-bet Transcription FactorT-Box Domain Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.