Evidence map›Paper›PMID 32632116›Full record

ArticleScientific reports2020

DoseGAN: a generative adversarial network for synthetic dose prediction using attention-gated discrimination and generation.

Vasant Kearney, Jason W Chan, Tianqi Wang, Alan Perry, Martina Descovich, Olivier Morin, Sue S Yom, Timothy D Solberg

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  4. Design and validation of a deep learning GAN for predictingJournal of applied clinical medical physics · 2026
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  9. A few-shot u-net learning framework for fast and accurate three-dimensional dose prediction in radiotherapy.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vasant Kearney *Department of Radiation Oncology, University of California, San Francisco, CA, 94115, USA. vasantkearney@gmail.com.
Jason W Chan *Department of Radiation Oncology, University of California, San Francisco, CA, 94115, USA.
Tianqi WangDepartment of Radiation Oncology, University of California, San Francisco, CA, 94115, USA.
Alan PerryDepartment of Radiation Oncology, University of California, San Francisco, CA, 94115, USA.
Martina DescovichDepartment of Radiation Oncology, University of California, San Francisco, CA, 94115, USA.
Olivier MorinDepartment of Radiation Oncology, University of California, San Francisco, CA, 94115, USA.ORCID http://orcid.org/0000-0002-9240-5704
Sue S YomDepartment of Radiation Oncology, University of California, San Francisco, CA, 94115, USA.ORCID http://orcid.org/0000-0002-0779-7476
Timothy D SolbergDepartment of Radiation Oncology, University of California, San Francisco, CA, 94115, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep learning algorithms have recently been developed that utilize patient anatomy and raw imaging information to predict radiation dose, as a means to increase treatment planning efficiency and improve radiotherapy plan quality. Current state-of-the-art techniques rely on convolutional neural networks (CNNs) that use pixel-to-pixel loss to update network parameters. However, stereotactic body radiotherapy (SBRT) dose is often heterogeneous, making it difficult to model using pixel-level loss. Generative adversarial networks (GANs) utilize adversarial learning that incorporates image-level loss and is better suited to learn from heterogeneous labels. However, GANs are difficult to train and rely on compromised architectures to facilitate convergence. This study suggests an attention-gated generative adversarial network (DoseGAN) to improve learning, increase model complexity, and reduce network redundancy by focusing on relevant anatomy. DoseGAN was compared to alternative state-of-the-art dose prediction algorithms using heterogeneity index, conformity index, and various dosimetric parameters. All algorithms were trained, validated, and tested using 141 prostate SBRT patients. DoseGAN was able to predict more realistic volumetric dosimetry compared to all other algorithms and achieved statistically significant improvement compared to all alternative algorithms for the V

Indexed as

AlgorithmsNeural Networks, ComputerHumansImage Processing, Computer-AssistedNeoplasmsRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-Assisted

Identifiers

PMID32632116
PMCPMC7338467

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.