Evidence map›Paper›PMID 32632093›Full record

ArticleNature communications2020

A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine.

Yanjun Guo, Pamela M Rist, Iyas Daghlas, Franco Giulianini, International Headache Genetics Consortium, 23andMe Research Team, Tobias Kurth, Daniel I Chasman

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 8 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 8 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
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  15. Article
  16. Circulation research · 2024
    Article
  17. Hallmarks of primary headache: part 1 - migraine.The journal of headache and pain · 2024
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 20 institutions in 13 countries.

Yanjun GuoDivision of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA. yguo19@bwh.harvard.edu.ORCID http://orcid.org/0000-0002-5927-778X
Pamela M RistDivision of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.
Iyas DaghlasDivision of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.
Franco GiulianiniDivision of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.
International Headache Genetics Consortium
23andMe Research Team
Tobias KurthDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02215, USA.
Daniel I ChasmanDivision of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA. dchasman@research.bwh.harvard.edu.
23andMe (United States) · USBroad Institute · USBrigham and Women's Hospital · USUniversity of Helsinki · FIUniversity of Tartu · EEErasmus MC · NLOslo University Hospital · NOUniversity of Copenhagen · DKdeCODE Genetics (Iceland) · ISHelsinki University Hospital · FILeiden University · NLQIMR Berghofer Medical Research Institute · AUUniversity of Bristol · GBKing's College London · GBVrije Universiteit Amsterdam · NLFinnish Institute for Health and Welfare · FIKarolinska Institutet · SEUniversity of Oulu · FIUniversity of Oxford · GBWashington University in St. Louis · US

Funding

PRE-DETERMINE: Biologic Markers and MRI SCD Cohort StudyR01HL091069 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ALBERT, CHRISTINE M · 2008 to 2020
$12.9M
Effects of Vitamin D and Omega-3 on Cerebrovascular DiseaseK01HL128791 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI RIST, PAMELA M. · 2016 to 2020
$858k
Causality and/or shared physiology linking plasma lipids and blood pressure to migraineR21NS104398 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI CHASMAN, DANIEL IAN · 2018 to 2019
$492k
NHLBI NIH HHS K01 HL128791NHLBI NIH HHS R01 HL091069NINDS NIH HHS R21 NS104398
6 · The paper itself

Abstract

Blood pressure (BP) was inconsistently associated with migraine and the mechanisms of BP-lowering medications in migraine prophylaxis are unknown. Leveraging large-scale summary statistics for migraine (N

Indexed as

Meta-Analysis as TopicPolymorphism, Single NucleotideBlood PressureEndoribonucleasesGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansHypertensionIntegrin beta ChainsMendelian Randomization AnalysisMigraine DisordersProteinsReceptors, Adrenergic, alpha-2Risk FactorsTelomeraseADRA2B protein, humanEndoribonucleasesIntegrin beta ChainsITGB5 protein, humanKIAA0040 protein, humanProteinsReceptors, Adrenergic, alpha-2SMG6 protein, humanTelomerase

Identifiers

PMID32632093
PMCPMC7338361
OpenAlexW3040251959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.