Evidence map›Paper›PMID 32632029›Full record

ArticleOccupational and environmental medicine2020

Exposure to cholinesterase inhibiting insecticides and blood glucose level in a population of Ugandan smallholder farmers.

Martin Rune Hassan Hansen, Erik Jørs, Annelli Sandbæk, Daniel Sekabojja, John C Ssempebwa, Ruth Mubeezi, Philipp Staudacher, Samuel Fuhrimann, Alex Burdorf, Bo Martin Bibby and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Occupational and environmental medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 5 countries.

Martin Rune Hassan HansenEnvironment, Work and Health, Danish Ramazzini Centre, Department of Public Health, Aarhus University, Aarhus, Denmark martinrunehassanhansen@ph.au.dk.ORCID 0000-0001-9681-2393
Erik JørsDepartment of Occupational and Environmental Medicine, Odense University Hospital, Odense, Denmark.
Annelli SandbækGeneral Practice, Department of Public Health, Aarhus University, Aarhus, Denmark.
Daniel SekabojjaUganda National Association of Community and Occupational Health, Kampala, Uganda.
John C SsempebwaSchool of Public Health, Makerere University, Kampala, Uganda.
Ruth MubeeziSchool of Public Health, Makerere University, Kampala, Uganda.
Philipp StaudacherEawag, Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, Switzerland.
Samuel FuhrimannInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0002-1861-1737
Alex BurdorfDepartment of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands.
Bo Martin BibbyBiostatistics, Department of Public Health, Aarhus University, Aarhus, Denmark.
Vivi SchlünssenEnvironment, Work and Health, Danish Ramazzini Centre, Department of Public Health, Aarhus University, Aarhus, Denmark.
Aarhus University · DKMakerere University · UGErasmus MC · NLETH Zurich · CHSteno Diabetes Centers · DKUniversity of Southern Denmark · DKUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe risk of diabetes mellitus may be elevated among persons exposed to some pesticides, including cholinesterase-inhibiting insecticides (organophosphates and carbamates). The objective of this study was to investigate how acetylcholinesterase activity was associated with mean blood glucose levels among smallholder farmers in Uganda.

methodsWe conducted a short-term follow-up study among 364 smallholder farmers in Uganda. Participants were examined three times from September 2018 to February 2019. At each visit, we measured glycosylated haemoglobin A (HbA

resultsContrary to our hypothesis, our mixed effect models showed significant correlation between low AChE/Hb and low HbA

conclusionsOur results do not clearly support a causal link between exposure to cholinesterase-inhibiting insecticides and elevated blood glucose levels (expressed as HbA

Indexed as

AdultBlood GlucoseCholinesterase InhibitorsFarmersFemaleHumansInsecticidesMaleMiddle AgedOccupational ExposureSurveys and QuestionnairesUgandaBlood GlucoseCholinesterase InhibitorsInsecticidesagriculturedeveloping countriesdiabetes mellitusepidemiologypesticides

Identifiers

PMID32632029
PMCPMC7509396
OpenAlexW3040161614

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.