Evidence map›Paper›PMID 32632025›Full record

ReviewGenetics2020

mRNA Editing, Processing and Quality Control in

Joshua A Arribere, Hidehito Kuroyanagi, Heather A Hundley

Open access · bronzeAbstract readReview
In one paragraph

Review in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. TheiScience · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Phylogenetic and structural analysis of Hydra ADAR.Archives of biochemistry and biophysics · 2025
    Article
  8. Article
  9. Article
  10. Molecular Mechanisms of Drug Resistance inPathogens (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Article
  13. ADR-2 regulates fertility and oocyte fate inbioRxiv : the preprint server for biology · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Attenuation of Dopaminergic Neurodegeneration in aJournal of developmental biology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Joshua A ArribereDepartment of MCD Biology, UC Santa Cruz, California 95064 jarriber@ucsc.edu kuroyana.end@tmd.ac.jp hahundle@indiana.edu.
Hidehito KuroyanagiLaboratory of Gene Expression, Medical Research Institute, Tokyo Medical and Dental University, Tokyo 113-8510, Japan, and jarriber@ucsc.edu kuroyana.end@tmd.ac.jp hahundle@indiana.edu.
Heather A HundleyMedical Sciences Program, Indiana University School of Medicine-Bloomington, Indiana 47405 jarriber@ucsc.edu kuroyana.end@tmd.ac.jp hahundle@indiana.edu.
Indiana University School of MedicineTokyo Medical and Dental University · JPUniversity of California, Santa Cruz · US

Funding

Mechanisms of Translational Surveillance in C. elegansR01GM131012 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Joshua Arribere · 2018 to 2026
$3.1M
Molecular mechanisms that regulate ADAR target recognition and RNA editing in vivoR01GM130759 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI HUNDLEY, HEATHER ANN · 2019 to 2023
$1.8M
NIGMS NIH HHS R01 GM130759NIGMS NIH HHS R01 GM131012
6 · The paper itself

Abstract

While DNA serves as the blueprint of life, the distinct functions of each cell are determined by the dynamic expression of genes from the static genome. The amount and specific sequences of RNAs expressed in a given cell involves a number of regulated processes including RNA synthesis (transcription), processing, splicing, modification, polyadenylation, stability, translation, and degradation. As errors during mRNA production can create gene products that are deleterious to the organism, quality control mechanisms exist to survey and remove errors in mRNA expression and processing. Here, we will provide an overview of mRNA processing and quality control mechanisms that occur in

Indexed as

Nonsense Mediated mRNA DecayRNA EditingAnimalsCaenorhabditis elegansRNA, MessengerRNA SplicingRNA, MessengerCaenorhabditis eleganspolyadenylationquality controlRNA editingRNA modificationsplicingWormBook

Identifiers

PMID32632025
PMCPMC7337075
OpenAlexW3038774435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.