ArticleProceedings of the National Academy of Sciences of the United States of America2020
Default-mode network streams for coupling to language and control systems.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07024875 (Precision Neuroimaging of Parkinson's Disease), which is not on this map. Cited by 103 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Precision Neuroimaging of Parkinson's Disease
Who cites it
103 citing papers in PubMed, 1 synthesis or guideline pooled it, 189 citations in OpenAlex.
- Tasks activating the default mode network map multiple functional systems.Brain structure & function · 2022Pooled it
- Intrinsic functional architecture predicts remote motor cortical excitability changes induced by intermittent theta-burst stimulation.iScience · 2026Article
- Precision fMRI reveals densely interdigitated network patches with conserved motifs in the lateral prefrontal cortex.Neuron · 2026Article
- Stronger right-hemispheric involvement in language processing is associated with greater functional connectivity between the left-lateralized language-related network and the cingulo-opercular network.Brain structure & function · 2026Article
- Feasibility of Precision Functional Mapping in Youth Multi-Echo fMRI Data.bioRxiv : the preprint server for biology · 2026Article
- Parallel processing chains span cytoarchitectures to organize association cortex.bioRxiv : the preprint server for biology · 2026Article
- Multimodal evidence for hippocampal engagement and modulation by functional connectivity-guided parietal TMS.Nature communications · 2026Article
- Commonality and Variability in Functional Networks in Children Under 5 Years Old.bioRxiv : the preprint server for biology · 2026Article
- Individualized Mapping of Functional Brain Networks in Older Adulthood.bioRxiv : the preprint server for biology · 2026Article
- Age-Related Differences in Resting-State Functional Connectivity Predict Specific Patterns of Speech Disfluency.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Benchmarking functional brain network organization in childhood and its similarity to adults.Frontiers in neuroimaging · 2026Article
- Convergent and divergent spatial topographies of individualized brain functional networks and their developmental origins.Psychoradiology · 2026Article
- Network-specific enhancement of global blood-oxygen-level-dependent signals and CSF coupling after language therapy in post-stroke aphasia.Brain communications · 2026Article
- Dense Phenotyping of Human Brain Network Organization Using Precision fMRI.Annual review of psychology · 2026Review
- The promise of infant MRI in psychiatry: toward a framework for neural network measures in early emotional and behavioral risk identification and new intervention targets.Molecular psychiatry · 2026Review
- Resting-State Coactivation Patterns of Language Reorganization in Brain Tumors.Neural plasticity · 2026Article
- Identifying left and right hemispheres using functional connectivity.bioRxiv : the preprint server for biology · 2025Article
- Functional differentiation and interactions among inferior, medial frontal and posterior temporal cortex in semantic control.Communications biology · 2025Article
- A Functional Resting-State Network Atlas Based on 420 Older Adults with Hypertension.bioRxiv : the preprint server for biology · 2025Article
- Mixed-Frequency rTMS Rapidly Modulates Multiscale EEG Biomarkers of Excitation-Inhibition Balance in Autism Spectrum Disorder: A Single-Case Report.Brain sciences · 2025Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 1 country.
Funding
Abstract
The human brain is organized into large-scale networks identifiable using resting-state functional connectivity (RSFC). These functional networks correspond with broad cognitive domains; for example, the Default-mode network (DMN) is engaged during internally oriented cognition. However, functional networks may contain hierarchical substructures corresponding with more specific cognitive functions. Here, we used individual-specific precision RSFC to test whether network substructures could be identified in 10 healthy human brains. Across all subjects and networks, individualized network subdivisions were more valid-more internally homogeneous and better matching spatial patterns of task activation-than canonical networks. These measures of validity were maximized at a hierarchical scale that contained ∼83 subnetworks across the brain. At this scale, nine DMN subnetworks exhibited topographical similarity across subjects, suggesting that this approach identifies homologous neurobiological circuits across individuals. Some DMN subnetworks matched known features of brain organization corresponding with cognitive functions. Other subnetworks represented separate streams by which DMN couples with other canonical large-scale networks, including language and control networks. Together, this work provides a detailed organizational framework for studying the DMN in individual humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.