Evidence map›Paper›PMID 32631846›Full record

ArticleJournal of epidemiology and community health2020

Alcohol consumption and internalising disorders in young adults of ALSPAC: a population-based study.

Gwen Sascha Fernandes, Gemma Lewis, Gemma Hammerton, Kushala Abeysekera, Liam Mahedy, Alexis Edwards, Glyn Lewis, Matthew Hickman, Jonathan Heron

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of epidemiology and community health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Gwen Sascha FernandesPopulation Health Sciences, University of Bristol School of Social and Community Medicine, Bristol, UK gwen.fernandes@bristol.ac.uk.ORCID 0000-0003-0203-7053
Gemma LewisUCL Division of Psychiatry, London, UK.
Gemma HammertonPopulation Health Sciences, University of Bristol School of Social and Community Medicine, Bristol, UK.
Kushala AbeysekeraPopulation Health Sciences, University of Bristol School of Social and Community Medicine, Bristol, UK.
Liam MahedyPopulation Health Sciences, University of Bristol School of Social and Community Medicine, Bristol, UK.
Alexis EdwardsVirginia Institute for Psychiatric and Behavior Genetics, Richmond, Virginia, USA.
Glyn LewisUCL Division of Psychiatry, London, UK.
Matthew HickmanSchool of Social and Community Medicine, University of Bristol, Bristol, UK.
Jonathan HeronSchool of Social and Community Medicine, University of Bristol, Bristol, UK.
University of Bristol · GBUniversity College Lahore · PKAmerican Psychiatric Foundation · US

Funding

The Etiology of Risk: Alcohol Use Disorder and Suicidal BehaviorR01AA027522 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Alexis C Edwards, Kristina Sundquist · 2019 to 2026
$3.5M
Genetic influences on developmental heterogeneity of alcohol use disorderK01AA021399 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI EDWARDS, ALEXIS C · 2012 to 2016
$707k
British Heart FoundationCancer Research UKMedical Research Council MC_PC_15018Medical Research Council MC_PC_19009Medical Research Council MR/KO232331/1Medical Research Council MR/L022206/1NIAAA NIH HHS K01 AA021399NIAAA NIH HHS R01 AA027522Wellcome TrustWellcome Trust 092731Wellcome Trust 204813/Z/16/ZWellcome Trust 209138/Z/17/Z
6 · The paper itself

Abstract

introductionDepression and harmful alcohol consumption contribute significantly to the global health burden, but in young adults, this relationship is under-researched and conflicted. The aim of this study was to determine the sex-based prevalence and the association between internalising disorders such as depression and alcohol use disorders.

methodUsing the Avon Longitudinal Study of Parents and Children, we assessed the sex-specific prevalence of International Classification of Diseases,Tenth Revision diagnosed generalised anxiety disorder (GAD), depression and fear-based anxieties (FBA) at 24 years (n=3572). We examined the association between internalising disorders and alcohol consumption using the Alcohol Use Disorder Identification Test for Consumption 5+ threshold and Diagnostic and Statistical Manual on Mental Disorders defined criteria for alcohol dependence.

resultsWomen reported more GAD (11.6% vs 6.5%), depression (13.4% vs 6.9%) and FBA (1.3% vs 0.5%) than men (p<0.001). Harmful drinking, after adjustment for sex and socioeconomic status, was associated with a higher prevalence of depression (OR 1.8, 95% CI 1.3 to 2.4, p<0.001), anxiety (OR 1.4, 95% CI 1.0 to 2.0, p<0.001) and FBA (OR 2.4, 95% CI 1.04 to 5.56, p=0.009) compared with lower-risk drinkers. In contrast, hazardous drinking was associated with a lower prevalence of GAD (OR 0.69, 95% CI 0.54 to 0.88) and depression (OR 0.68, 95% CI 0.54 to 0.86) compared with lower-risk drinkers.

conclusionsYoung adults in the UK who drink harmfully are more likely to have depression and other internalising disorders. Further research should test whether there is a J-shaped relationship between alcohol consumption and mental health in young people and whether this varies across the life course.

Indexed as

AlcoholismAdolescentAlcohol DrinkingAnxiety DisordersDepressionFemaleHumansLongitudinal StudiesMaleUnited KingdomYoung Adultaddictive behaviour/addictionalcoholDepressionepidemiology

Identifiers

PMID32631846
PMCPMC8886795
OpenAlexW3035044628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.