Evidence map›Paper›PMID 32631830›Full record

ArticleDevelopment (Cambridge, England)2020

Ecdysone-dependent feedback regulation of prothoracicotropic hormone controls the timing of developmental maturation.

Christian F Christensen, Takashi Koyama, Stanislav Nagy, E Thomas Danielsen, Michael J Texada, Kenneth A Halberg, Kim Rewitz

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Optogenetic control of transition to metamorphosis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Artificial light at night (ALAN) negatively affects expression of transcripts involved in biosynthesis of molting and juvenile hormones in Bombyx mori.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  5. A dynamical model of growth and maturation inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Christian F ChristensenDepartment of Biology, University of Copenhagen, 2100 Copenhagen O, Denmark.ORCID 0000-0003-0550-4948
Takashi KoyamaDepartment of Biology, University of Copenhagen, 2100 Copenhagen O, Denmark.ORCID 0000-0003-4203-114X
Stanislav NagyDepartment of Biology, University of Copenhagen, 2100 Copenhagen O, Denmark.
E Thomas DanielsenDepartment of Biology, University of Copenhagen, 2100 Copenhagen O, Denmark.ORCID 0000-0002-5139-5466
Michael J TexadaDepartment of Biology, University of Copenhagen, 2100 Copenhagen O, Denmark.ORCID 0000-0003-2479-1241
Kenneth A HalbergDepartment of Biology, University of Copenhagen, 2100 Copenhagen O, Denmark.ORCID 0000-0002-5903-7196
Kim RewitzDepartment of Biology, University of Copenhagen, 2100 Copenhagen O, Denmark kim.rewitz@bio.ku.dk.ORCID 0000-0002-4409-9941
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The activation of a neuroendocrine system that induces a surge in steroid production is a conserved initiator of the juvenile-to-adult transition in many animals. The trigger for maturation is the secretion of brain-derived neuropeptides, yet the mechanisms controlling the timely onset of this event remain ill-defined. Here, we show that a regulatory feedback circuit controlling the

Indexed as

AnimalsBody SizeDrosophilaDrosophila ProteinsEcdysteroneGene Expression Regulation, DevelopmentalInsect HormonesLarvaMetamorphosis, BiologicalMicroscopy, FluorescenceNeuronsReceptors, SteroidRNA, Guide, CRISPR-Cas SystemsRNA InterferenceSignal TransductionDrosophila Proteinsecdysone receptorEcdysteroneInsect Hormonesprothoracicotropic hormoneReceptors, SteroidRNA, Guide, CRISPR-Cas SystemsDrosophilaEcdysoneMaturationProthoracicotropicPtthSteroid

Identifiers

PMID32631830
PMCPMC7390634
OpenAlexW3039391304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.