Observational studyThe Journal of thoracic and cardiovascular surgery2022
Determinants of hospital variability in perioperative red blood cell transfusions during coronary artery bypass graft surgery.
Observational study in The Journal of thoracic and cardiovascular surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Safety and Efficacy of Tranexamic Acid in General Surgery.JAMA surgery · 2025Trial
- Pre-operative anaemia, red blood cell transfusion and mortality after cardiac surgery: a Netherlands Heart Registration mediation analysis.Anaesthesia · 2026Article
- Intraoperative allogeneic packed red blood cell transfusions and postoperative delirium: a retrospective cohort study in the USA.EClinicalMedicine · 2026Article
- Compliance with ESAIC guidelines for fibrinogen concentrate prescription in cardiac surgery: a multicentre French cohort study.BMC anesthesiology · 2025Observational
- The imperative integration of patient blood management into ERACS: bridging the gap for optimizing outcomes in cardiac surgery.Perioperative medicine (London, England) · 2025Review
- Review
- Impact of zero-positive end-expiratory pressure on blood transfusion rates in off-pump coronary artery bypass surgery: a retrospective cohort study.BMC anesthesiology · 2024Article
- Sex Differences in Red Blood Cell Transfusions and 30-Day Mortality in Cardiac Surgery: A Single Center Observational Study.Journal of clinical medicine · 2023Article
- Adult Clinical Perfusion Practice Survey: 2020 results.The journal of extra-corporeal technology · 2023Article
- Cardiopulmonary bypass in a rat model may shorten the lifespan of stored red blood cells by activating caspase-3.PloS one · 2023Article
- Commentary: Culture trumps (transfusion) guidelines.The Journal of thoracic and cardiovascular surgery · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectiveTo identify to what extent distinguishing patient and procedural characteristics can explain center-level transfusion variation during coronary artery bypass grafting surgery.
methodsObservational cohort study using the Perfusion Measures and Outcomes Registry from 43 adult cardiac surgical programs from July 1, 2011, to July 1, 2017. Iterative multilevel logistic regression models were constructed using patient demographic characteristics, preoperative risk factors, and intraoperative conservation strategies to progressively explain center-level transfusion variation.
resultsOf the 22,272 adult patients undergoing isolated coronary artery bypass surgery using cardiopulmonary bypass, 7241 (32.5%) received at least 1 U allogeneic red blood cells (range, 10.9%-59.9%). When compared with patients who were not transfused, patients who received at least 1 U red blood cells were older (68 vs 64 years; P < .001), were women (41.5% vs 15.9%; P < .001), and had a lower body surface area (1.93 m
conclusionsThe results suggest that variation in center-level red blood cells transfusion cannot be explained by patient and procedural factors alone. Investigating organizational culture and programmatic infrastructure may be necessary to better understand variation in transfusion practices.
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