Trial reportBMC pregnancy and childbirth2020
Effects of pre-pregnancy body mass index and gestational weight gain on maternal and infant complications.
Trial report in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03403543 (Chinese Pregnant Woman Cohort Study), which is not on this map. Cited by 162 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chinese Pregnant Woman Cohort Study
Who cites it
162 citing papers in PubMed, 12 syntheses or guidelines pooled it, 321 citations in OpenAlex.
- Double Burden of Malnutrition Prevalence in Pregnant Women: Systematic Review and Meta-Analysis.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026Pooled it
- Association between 6:2 chlorinated polyfluoroalkyl ether sulfonic acid exposure and glucolipid metabolism in Chinese adults: a meta-analysis.Systematic reviews · 2026Pooled it
- Long-term metabolic consequences ofFrontiers in endocrinology · 2026Pooled it
- Pregnancy Outcomes Following Different Types of Bariatric Surgery: A Network Meta-Analysis.Obesity surgery · 2025Pooled it
- Maternal adiposity measures and hypertensive disorders of pregnancy: a meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- The association between ultra-processed food and common pregnancy adverse outcomes: a dose-response systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- Pooled it
- Pooled it
- The Efficacy and Safety of Myo-inositol Supplementation for the Prevention of Gestational Diabetes Mellitus in Overweight and Obese Pregnant Women: A Systematic Review and Meta-Analysis.Journal of the ASEAN Federation of Endocrine Societies · 2023Pooled it
- Maternal Consumption of Ultra-Processed Foods-Rich Diet and Perinatal Outcomes: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- Impacts of Consumption of Ultra-Processed Foods on the Maternal-Child Health: A Systematic Review.Frontiers in nutrition · 2022Pooled it
- Pregnancy-related complications and perinatal outcomes following progesterone supplementation before 20 weeks of pregnancy in spontaneously achieved singleton pregnancies: a systematic review and meta-analysis.Reproductive biology and endocrinology : RB&E · 2021Pooled it
- Physical activity, gestational weight gain in obese patients with early gestational diabetes and the perinatal outcome - a randomised-controlled trial.BMC pregnancy and childbirth · 2024Trial
- Dietary treatment postpartum in women with obesity reduces weight and prevents weight gain: a randomised controlled trial.BMC pregnancy and childbirth · 2023Trial
- Gestational diabetes status modifies pre-pregnancy BMI associations with large for gestational age: A prospective cohort study in central China.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Late-pregnancy air pollution exposure and neonatal anthropometry with and without gestational hypertension.iScience · 2026Article
- The Expanded Biopsychosocial Model Elucidates the Association Between Pre-Pregnancy Overweight/Obesity and Delayed Lactogenesis II: A Prospective Cohort Study.Maternal & child nutrition · 2026Article
- Article
- Restricted cubic spline analysis of the association between the third-trimester triglyceride-glucose index and neonatal birthweight in pregnant women with gestational diabetes mellitus: a multicenter cohort study.BMC pregnancy and childbirth · 2026Article
- The causality between physical activity and gestational diabetes mellitus: a Mendelian randomization study.Molecular genetics and genomics : MGG · 2026Article
102 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe potential effects of pre-pregnancy body mass (BMI) and gestational weight gain (GWG) on pregnancy outcomes remain unclear. Thus, we investigated socio-demographic characteristics that affect pre-pregnancy BMIs and GWG and the effects of pre-pregnancy BMI and GWG on Chinese maternal and infant complications.
methods3172 women were enrolled in the Chinese Pregnant Women Cohort Study-Peking Union Medical College from July 25, 2017 to July 24, 2018, whose babies were delivered before December 31, 2018. Regression analysis was employed to evaluate the socio-demographic characteristics affecting pre-pregnancy BMI and GWG values and their effects on adverse maternal and infant complications.
resultsMultivariate logistic regression analysis revealed that age groups < 20 years (OR: 1.97), 25-30 years (OR: 1.66), 30-35 years (OR: 2.24), 35-40 years (OR: 3.90) and ≥ 40 years (OR: 3.33) as well as elementary school or education below (OR: 3.53), middle school (OR: 1.53), high school (OR: 1.40), and living in the north (OR: 1.37) were risk factors in maintaining a normal pre-pregnancy BMI. An age range of 30-35 years (OR: 0.76), living in the north (OR: 1.32) and race of ethnic minorities (OR: 1.51) were factors affecting GWG. Overweight (OR: 2.01) and inadequate GWG (OR: 1.60) were risk factors for gestational diabetes mellitus (GDM). Overweight (OR: 2.80) and obesity (OR: 5.42) were risk factors for gestational hypertension (GHp). Overweight (OR: 1.92), obesity (OR: 2.48) and excessive GWG (OR: 1.95) were risk factors for macrosomia. Overweight and excessive GWG were risk factors for a large gestational age (LGA) and inadequate GWG was a risk factor for low birth weights.
conclusionsOverweight and obesity before pregnancy and an excessive GWG are associated with a greater risk of developing GDM, GHp, macrosomia and LGA. The control of body weight before and during the course of pregnancy is recommended to decrease adverse pregnancy outcomes, especially in pregnant women aged < 20 or > 25 years old educated below university and college levels, for ethnic minorities and those women who live in the north of China.
trial registrationRegistered at Clinical Trials ( NCT03403543 ), September 29, 2017.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.