SynthesisBMC cardiovascular disorders2020
Physical activity and the risk of sudden cardiac death: a systematic review and meta-analysis of prospective studies.
Synthesis in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Physical activity and the risk of cataract and age-related macular degeneration: a systematic review and meta-analysis of cohort studies.BMC ophthalmology · 2026Pooled it
- Cardiorespiratory fitness is a strong and consistent predictor of morbidity and mortality among adults: an overview of meta-analyses representing over 20.9 million observations from 199 unique cohort studies.British journal of sports medicine · 2024Pooled it
- Risk and Protective Factors for Sudden Cardiac Death: An Umbrella Review of Meta-Analyses.Frontiers in cardiovascular medicine · 2022Pooled it
- Trends and Demographic Disparities Among Adults With Sudden Cardiac Death and Diabetes Mellitus in the United States: A Nationwide Analysis.Journal of arrhythmia · 2026Article
- Vigorous exertion, regular exercise training, and the risk of sudden cardiac death due to myocardial infarction in Swedish men.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Equine models in translational medicine: A comparative approach to human health.Animal models and experimental medicine · 2026Review
- Leisure-time physical activity and risk of sudden cardiac death: a 28-year follow-up from the Copenhagen City Heart Study.EClinicalMedicine · 2026Article
- Physical function, daily activities, and spinal pain in the elderly: A cross-sectional study.PloS one · 2026Article
- Higher cardiorespiratory fitness levels attenuate but do not negate the heightened risk of sudden cardiac death due to obesity: A prospective cohort study.International journal of cardiology. Heart & vasculature · 2025Article
- Protecting the Heart in Motion: The Role of Physical Activity and Cardiorespiratory Fitness in Preventing Sudden Cardiac Death.Clinical Medicine Insights. Cardiology · 2025Review
- The Interplay of Type 2 Diabetes Status, Cardiorespiratory Fitness Level, and Sudden Cardiac Death: A Prospective Cohort Study.CJC open · 2024Article
- A retrospective analysis of serious adverse events and deaths in U.S.-based lifestyle clinical trials for cognitive health.Contemporary clinical trials communications · 2024Article
- Acute myocardial infarction following "dry scooping" of a pre-workout supplement in a healthy young man of African origin: A case report.SAGE open medical case reports · 2024Article
- Physical activity modification over time according to socioeconomic position: results from the EPIC-Italy cohort study.BMJ open sport & exercise medicine · 2024Article
- Traditional Uses, Phytochemistry, and Pharmacological Activities ofCurrent pharmaceutical design · 2024Review
- Family history, socioeconomic factors, comorbidities, health behaviors, and the risk of sudden cardiac arrest.Scientific reports · 2023Article
- Sudden Cardiac Death: A Systematic Review.Cureus · 2023Review
- Sudden Cardiac Death: An Update on Commotio Cordis.Cureus · 2023Review
- Interaction effects between insomnia and depression on risk of out-of-hospital cardiac arrest: Multi-center study.PloS one · 2023Article
- Dynamic Change of Cardiovascular Health Metrics and Long-Term Risk of Sudden Cardiac Death: The ARIC Study.Journal of the American Heart Association · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundPhysical activity has been associated with a significant reduction in risk of sudden cardiac death in epidemiological studies, however, the strength of the association needs clarification. We conducted a systematic review and meta-analysis to summarize the available data from population-based prospective studies.
methodsPubMed and Embase databases were searched for studies of physical activity and sudden cardiac death from inception to March 26th 2019. Prospective studies reporting adjusted relative risk (RR) estimates and 95% confidence intervals (CIs) of sudden cardiac death associated with physical activity were included. A random effects model was used to estimate summary RRs (95% CIs).
resultsThirteen prospective studies were included in the systematic review. Eight prospective studies with 1193 sudden cardiac deaths among 136,298 participants were included in the meta-analysis of physical activity and sudden cardiac death and the summary RR for highest vs. lowest level of physical activity was 0.52 (95% CI: 0.45-0.60, I
conclusionThis meta-analysis suggest that a high compared to a low level of physical activity may reduce the risk of sudden cardiac death in the general population. Further studies are needed to clarify the dose-response relationship between specific subtypes and intensities of physical activity in relation to sudden cardiac death.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.